Carcinoma of the colon and rectum in persons under twenty years of age

Colorectal adenocarcinoma in childhood and adolescent

“…A palpable abdominal mass may be noted in some patients [10]. In our series, pain and vomiting were the most frequent symptoms (six cases each), followed by diarrhea (five cases), enterorragia (four cases), weight toss (two cases), alimentary intolerance (two ~cases) and bowel rhythm alteration (two cases).…”

“…Not infrequently the first sign of a right colon neoplasm will be an accidental discovery of a mass [10] and they do not usually produce obstruction. Complete obstruction may be the first sign of a colonic tumor and acute suppurative appendicitis has been reported due to primitive or metastatic colon cancer that obstructed the basis of the appendix [10,37]. This finding was observed in three of our cases.…”

“…Age is no barrier to the occurrence of carcinoma of the colon and rectum [10]. While for adults they are one of the most common visceral malignancies in the US [29], tumors arising in children's large intestine usually account for less than 1% of the total [21,30,31].…”

Primary Solid Tumors of the Colon and Rectum in the Pediatric Patient: A Review of 270 Cases

“…Signet ring histology had the worst disease-free survival (DFS) at 18.5% 5-y and 17.0% 10-y, yet this was still improved from reports in the current literature. Furthermore, it has been shown that pediatric patients present with higher grade tumors than their adult counterparts [17][18][19][20][21][22][23]. Similarly, our analysis demonstrated that colorectal cancers among the pediatric patient have a predilection for advanced disease among mucinous and signet ring subtypes.…”

Carcinoma of the colon: diagnosis by ultrasound and enema

“…Pain referred to the umbilical region may be considered inconsequential childhood colic [8]. A mistaken diagnosis of appendicitis as occurred in our second case is not uncommon [9,10]. In many cases the diagnosis is not initially considered.…”