Carcinoma of the Extrahepatic Biliary Tract

Longmire, William P.; McArthur, Michael S.; Bastounis, Elias; Hiatt, Jonathan R.

doi:10.1097/00000658-197309000-00013

Cited by 186 publications

(69 citation statements)

References 8 publications

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“…These results were confirmed by other series [3][4][5][6]11,16,17,[23][24][25][26][27][28][29][30][31][32] and by the French collective survey of extrahepatic bile duct cancer. Our series of 40 resections from one institution reflects the long-term results of this policy.…”

Section: Discussionsupporting

confidence: 80%

Proximal Bile Duct Cancer: High Resectability Rate and 5-Year Survival

Launois¹,

Terblanche²,

Lakéhal³

et al. 1999

Annals of Surgery

141

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Section: Discussionsupporting

confidence: 80%

Proximal Bile Duct Cancer: High Resectability Rate and 5-Year Survival

Launois¹,

Terblanche²,

Lakéhal³

et al. 1999

Annals of Surgery

141

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“…Extrahepatic bile duct cancer is classified as proximal, middle, or distal bile duct cancer according to the anatomical location of the tumor in the biliary tree [1,2]. The middle bile duct is defined as the distal half of the extrahepatic bile duct, and the distal bile duct is referred to as the intrapancreatic bile duct [2].…”

Section: Introductionmentioning

confidence: 99%

The survival outcome and prognostic factors for middle and distal bile duct cancer following surgical resection

Choi

Park

Kim

et al. 2009

Journal of Surgical Oncology

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“…3 Extrahepatic (EH)-CCC arises from the biliary tree outside the liver parenchyma and also has been referred to as bile duct carcinoma, hilar, or central CCC. EH-CCCs classically have been described according to the classification of Longmire et al, 6 which separates tumors into the proximal one third (also known as Klatskin-type 5 ), middle one third, and distal one third lesions.…”

mentioning

confidence: 99%

Liver transplantation for cholangiocellular carcinoma: Analysis of a single-center experience and review of the literature

Shimoda

Farmer

Colquhoun

et al. 2001

Liver Transplantation

204

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Cholangiocellular carcinoma (CCC) is a biliary malignancy that frequently presents in advanced unresectable stages. The role of liver transplantation (LT) as a surgical modality is unclear. The goal of this study is to evaluate outcomes of patients with CCC undergoing LT. A retrospective analysis of all patients undergoing LT was undertaken. Only those patients with the pathological diagnosis of CCC were included on the study. Patients were divided into two groups based on primary tumor location: extrahepatic (EH)-CCC and intrahepatic (IH)-CCC. The Kaplan-Meier method was used to calculate overall and recurrence-free survival. Log-rank analysis was used to determine the significance of prognostic variables. Twenty-five patients were identified: 9 patients with EH-CCC (5 patients, Klatskin-type; 2 patients, the middle third; and 2 patients, the distal third) and 16 patients with IH-CCC. Mean age was 47.1 ؎ 10.6 years. There were 14 men and 11 women. Tumor stage was local (stages I and II; n ‫؍‬ 9) or advanced (stages III and IV; n ‫؍‬ 16). Overall and disease-free survival rates were 71% and 67% at 1 year and 35% and 32% at 3 years, respectively. Analysis of variables showed statistically significant improved outcomes (P < .05) for the absence of contiguous organ invasion at LT, small tumor size, and single tumor foci. This study indicates that early survival after LT for CCC is acceptable. Three-year disease-free survival is achieved in approximately 30% of patients. These outcomes can be improved by applying strict selection criteria based on prognostic variables identified in this study. (Liver Transpl 2001;7:1023-1033.)

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Carcinoma of the Extrahepatic Biliary Tract

Cited by 186 publications

References 8 publications

Proximal Bile Duct Cancer: High Resectability Rate and 5-Year Survival

Proximal Bile Duct Cancer: High Resectability Rate and 5-Year Survival

The survival outcome and prognostic factors for middle and distal bile duct cancer following surgical resection

Liver transplantation for cholangiocellular carcinoma: Analysis of a single-center experience and review of the literature

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