Carcinoma of the pharyngeal pouch

Stevens, Dennis J.

doi:10.1017/s0022215100109776

Cited by 13 publications

(11 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Outcomes are usually quoted as dismal because of a delayed diagnosis. In fact, most cases are advanced tumors at the time of the operation 7,10,18,40 . However, several cases of superficial carcinoma have been described 26,28,37,40,45,47 …”

Section: Methodsmentioning

confidence: 99%

“…Several cases of carcinoma in previously treated diverticula have been reported, especially after endoscopic treatment 7,20,27,34,47 . Very interestingly, however, a carcinoma may develop in treated diverticula, even after resection 7,20,23,27,34,47,48 …”

Section: Methodsmentioning

confidence: 99%

“…In addition, the risk of malignancy has also been described; even though the true risk is still elusive. The carcinogeneses may be caused by chronic irritation by food, inflammation and repeated injury, 5–7 a pathogenesis similar to that of achalasia 8 …”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Esophageal diverticula and cancer

Herbella

Dubecz

Patti

2011

Diseases of the Esophagus

View full text Add to dashboard Cite

Esophageal diverticula are rare. The association of cancer and diverticula has been described. Some authors adopt a conservative non-surgical approach in selected patients with diverticula whereas others treat the symptoms by diverticulopexy or myotomy only, leaving the diverticulum in situ. However, the risk of malignant degeneration should be may be taken in account if the diverticulum is not resected. The correct evaluation of the possible risk factors for malignancy may help in the decision making process. We performed a literature review of esophageal diverticula and cancer. The incidence of cancer in a diverticulum is 0.3-7, 1.8, and 0.6% for pharyngoesophageal, midesophageal, and epiphrenic diverticula, respectively. Symptoms may mimic those of the diverticulum or underlying motor disorder. Progressive dysphagia, unintentional weight loss, the presence of blood in the regurgitated material, regurgitation of peaces of the tumor, odynophagia, melena, hemathemesis, and hemoptysis are key symptoms. Risk factors for malignancy are old age, male gender, long-standing history, and larger diverticula. A carcinoma may develop in treated diverticula, even after resection. Outcomes are usually quoted as dismal because of a delayed diagnosis but several cases of superficial carcinoma have been described. The treatment follows the same principals as the therapy for esophageal cancer; however, diverticulectomy is enough in cases of superficial carcinomas. Patients must be carefully evaluated before therapy and a long-term follow-up is advisable.

show abstract

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Esophageal diverticula and cancer

Herbella

Dubecz

Patti

2011

Diseases of the Esophagus

View full text Add to dashboard Cite

show abstract

“…Des Weiteren wird die fehlende histologische Untersuchung des Divertikels als problematisch angesehen. In der Literatur sind jedoch bislang lediglich 5 Fälle eines Divertikelkarzinoms nach transoralem Vorgehen beschrieben worden, welche nach einer postoperativen Latenzphase von 2 bis 13 Jahren diagnostiziert wurden [12,52,71,88,106]. Auûerdem unterbleibt die histologische Untersuchung auch bei konventionellen Verfahren wie Invagination, Pexie und alleiniger Myotomie.…”

Section: Schlussfolgerungenunclassified

Aktuelle Behandlungskonzepte des Zenker- Divertikels - Indikationen und Ergebnisse

Colombo-Benkmann

Unruh²,

Kocher³

et al. 2003

Zentralbl Chir

View full text Add to dashboard Cite

Conventional transcervical therapy of Zenker's diverticulum comprises diverticulectomy, invagination, diverticulopexy and myotomy, which may be combined with the aforementioned methods. Transoral diverticuloesophagostomy is performed by diathermy, lasers or staplers through a rigid esophagoscope, or more recently by diathermy applied via a flexible endoscope. Morbidity of transcervical procedures ranges between 3 (myotomy) and 23 % (diverticulectomy + myotomy). The percentage of patients with at least significantly improved symptoms is 92 % or more, while recurrences occur in 5.7 (diverticulectomy alone) to 21 % (invagination). Transoral procedures have a morbidity of 9 (stapler) to 26 % (Laser), while symptoms improve in 91 (diathermy through rigid esophagoscope) to 99 % (diathermy via flexible endoscope), however in up to 64 % of patients reoperations are necessary. Small diverticula (Brombart I/II) can be treated by diverticulectomy (with/without myotomy) or flexible endoscopy, larger diverticula in general by all methods. Patients younger than 60 years should undergo diverticulectomy, elderly multimorbid patients should be treated by transoral procedures.

show abstract

“…There have been reports in the literature of carcinoma developing in long‐standing, untreated pouches 1 and also in pouches that have previously been treated by surgical methods. These latter reports have involved patients who have had either pharyngeal pouch excision by external approach 2–4 or by Dohlman's procedure 5–8 . Endoscopic stapling is currently the procedure of choice for the surgical treatment of pharyngeal pouches 9 and to the best of our knowledge has never previously been reported to be associated with the subsequent development of a carcinoma in the pouch remnant.…”

Section: Introductionmentioning

confidence: 99%