Abstract:Non metastatic neurological concomitants of tumors are well known. They include an amyotrophic lateral sclerosis (ALS)-like syndrome in association with various tumors. The association with prostatic carcinoma is very rare. The case reported here seems to confirm the outcome of epidemiological research: the association is fortuitous.
“…Among the reported cases have been limbic encephalitis,5 – 7 cerebellar degeneration,8 9 the syndrome of inappropriate antidiuretic hormone10 11 and peripheral neuropathy with anti-Hu antibodies 12. Motor neuron disease has also been reported in association with prostate cancer13 and dermatomyositis 14…”
This unique paraneoplastic syndrome chiefly affecting the brainstem may be a diagnostic clue to the presence of unsuspected prostate adenocarcinoma. Further studies will be required to determine the precise antigenic target.
“…Among the reported cases have been limbic encephalitis,5 – 7 cerebellar degeneration,8 9 the syndrome of inappropriate antidiuretic hormone10 11 and peripheral neuropathy with anti-Hu antibodies 12. Motor neuron disease has also been reported in association with prostate cancer13 and dermatomyositis 14…”
This unique paraneoplastic syndrome chiefly affecting the brainstem may be a diagnostic clue to the presence of unsuspected prostate adenocarcinoma. Further studies will be required to determine the precise antigenic target.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.