Carcinoma of the Seminal Vesicle

Smith, Baxter A.; Webb, Edgar A.; Price, William E.

doi:10.1016/s0022-5347(17)63110-0

Cited by 30 publications

(9 citation statements)

References 6 publications

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“…Intravenous urography might be normal or show non‐specific findings such as ureteral displacement and elevation of the bladder base. Seminal vesiculography might show obliteration, deformity or filling defect in the gland 7 . The advent of modern cross‐sectional imaging has vastly improved the detection of seminal vesicle lesions.…”

Section: Discussionmentioning

confidence: 99%

Imaging of primary leiomyosarcoma of the seminal vesicle

Upreti

Bhargava

Kumar

2003

Australasian Radiology

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Leiomyosarcoma of the seminal vesicle is exceedingly rare. The ultrasound and CT findings in a recent case are described. These consist of a mass causing enlargement of the right seminal vesicle with involvement of the urinary bladder and prostate. The prostate gland was displaced inferiorly and to the left. Surgical resection and subsequent histology confirmed the diagnosis. The role of imaging in retrovesical masses is also discussed.

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Section: Discussionmentioning

confidence: 99%

Imaging of primary leiomyosarcoma of the seminal vesicle

Upreti

Bhargava

Kumar

2003

Australasian Radiology

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“…Complete excision is the mainstay for primary treatment, providing the best prognosis. [ 2 , 6 , 18 ] However, operating on PSVA is difficult due to its cystic structure and complicated anatomical relationships with the surrounding tissue. Moreover, it is still debated whether to prophylactically resect draining lymph nodes.…”

Section: Discussionmentioning

confidence: 99%

A 5-year follow-up of primary seminal vesicle adenocarcinoma

Yin

Jiang

2018

Medicine

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Rationale:Primary seminal vesicle adenocarcinoma (PSVA) is an extremely rare malignancy that should be carefully differentiated from cancer originating in the prostate, colon or bladder. Without standard guidelines, radical resection is considered a mainstay treatment, providing the best prognosis. However, as manifestations of PSVA are not detected in early stages, the majority of cases of PSVA are diagnosed at late stages, contributing to poor prognosis.Patient concerns:We described the case of a PSVA patient confirmed by histopathology and immunohistochemistry (IHC) staining positive for carbohydrate antigen-125 (CA-125) and negative for prostate specific antigen (PSA).Diagnosis:Primary seminal vesicle adenocarcinoma.Interventions:Surgery was carried out at the beginning, however, residual tumor was verified; thus 3 cycles of chemotherapy with a regimen of paclitaxel and cis-platinum were performed, followed by radical pelvic radiotherapy with a dose of 60 Gray in 30 fractions; then, another 3 cycles of the same chemotherapy were carried out.Outcomes:At the moment, the patient is still under follow-up and has been disease-free for more than 5 years.Lessons:Our manuscript describes a patient with PSVA with long-term survival and supplies a successful management strategy for this malignancy.

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“…Radical surgery is the mainstay primary therapy, offering the best survival rates. 1,2,20 Radiotherapy has been used as adjuvant treatment in case of inadequate resection or positive margins. 12,16 The role of chemotherapy is controversial.…”

Section: Discussionmentioning

confidence: 99%

Primary Bilateral Seminal Vesicle Carcinoma

et al. 2012

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With no more than 60 reported cases, tumors of the seminal vesicles are rare. Because of poor and nonspecific symptoms diagnosis is often very difficult. This report presents a case of a 56-year-old man with right renal agenesis and intermittent hematospermia and bilateral cystic masses of the seminal vesicles. Transrectal biopsies of the cystic lesion revealed a papillary clear cell adenocarcinoma. The patient underwent radical prostatectomy and pelvic lymphoadenectomy. Lymph node metastases were found on histological examination. The patient received 4 cycles of chemotherapy and pelvic radiotherapy. He remains disease free 21 months after surgery. Radiological imaging in patients with hematospermia and hematuria will allow disease detection at earlier stages. Immunohistochemistry and histomorphology can be used for differential diagnosis. Surgery with clear margins offers the best chance to cure. Hormonal and radio-chemotherapy have a role as adjuvant and palliative treatment.

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Carcinoma of the Seminal Vesicle

Cited by 30 publications

References 6 publications

Imaging of primary leiomyosarcoma of the seminal vesicle

Imaging of primary leiomyosarcoma of the seminal vesicle

A 5-year follow-up of primary seminal vesicle adenocarcinoma

Primary Bilateral Seminal Vesicle Carcinoma

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