Carcinoma of the thoracic esophagus

Maillet, P; Baulieux, J.; Boulez, J.; Benhaim, R

doi:10.1016/0002-9610(82)90181-7

Cited by 25 publications

(3 citation statements)

References 17 publications

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“…Many studies concerning the prognosis of patients with squamous cell carcinoma of the esophagus undergoing esophagectomy have been reported, most of which noted that prognosis of the patients depends on whether the resection was curative or palliative [1,[5][6][7][8][9]24]. The second major prognostic factor was reported to be lymph node metastasis.…”

Section: Discussionmentioning

confidence: 99%

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Esophageal squamous cell carcinoma: Pathology and prognosis

et al. 1994

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Between 1985 and 1992 a total of 403 patients with resected thoracic esophageal squamous cell carcinoma were evaluated histopathologically, and various pathologic findings related to survival were examined. Concerning depth of tumor invasion, 8 (2%) cases were pTis, 110 (27%) were pT1, 48 (12%) were pT2, 202 (50%) were pT3, and 35 (9%) were pT4. Lymphatic invasion was detected in 299 cases (74%), blood vessel invasion in 200 cases (49%), intramural metastasis in 45 (11%), and lymph node metastasis in 232 (58%). In pT1 carcinoma cases, 4% of mucosal carcinomas and 30% of submucosal carcinomas had lymph node metastasis. Tumors with deeper invasion had a higher incidence of lymph node metastasis: 74% of pT3 carcinomas and 83% of pT4 carcinomas. The sites of lymph node metastasis were divided into mediastinal, cervical, and abdominal fields; and rates of lymph node metastasis were 49%, 14%, and 41%, respectively. In all resected cases, the operative mortality rate was 3.2%, and the overall 5-year survival rate was 44.8%. The 5-year survival rate of patients with curative resection (R0 and R1) was 49.5%, whereas patients with palliative resection (R2) did not survive more than 3 years. There was no significant difference in survival relative to tumor location. In curatively resected cases, the significant prognostic factors by multivariate analysis were pT category, vascular invasion, lymph node metastasis, and intramural metastasis. Prognosis of lymph node-positive cases did not depend on the positive node site. Patients with only one positive node had a better prognosis, and those with six or more positive nodes had a poor prognosis.(ABSTRACT TRUNCATED AT 250 WORDS)

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Section: Discussionmentioning

confidence: 99%

“…The 5-year survival rate of patients whose esophageal carcinomas were resected before 1980 was low, varying from 7% to 28% [1][2][3][4][5][6][7][8][9][10]. For those with thoracic esophageal carcinoma, lymph node metastasis was frequently noted to extend from the superior mediastinum to the celiac region.…”

mentioning

confidence: 99%

Esophageal squamous cell carcinoma: Pathology and prognosis

et al. 1994

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“…Esophageal resection and reconstruction is now a safe procedure, and the 30 day mortality is under 5% [3,4,1 I , 121. Intrathoracic anastomosis [ 1,2,13], antethoracic reconstruction [ 81, or retrosternal reconstruction [ 141 is usually performed, depending on the surgeon's preference. One of the greatest advantages of intrathoracic anastomosis is that a long esophageal substitute is not needed, since, with only about 23 cm, the gastric tube can be pulled up to the upper mediastinum.…”

Section: Discussionmentioning

confidence: 99%

Safety of EEA staplers for anastomosis between upper esophagus and the gastric tube

Sugimachi

Ohno

Maekawa

et al. 1990

Journal of Surgical Oncology

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The EEA stapling devices used for intrathoracic anastomosis between the upper esophagus and the gastric tube in patients with carcinoma of the thoracic esophagus were evaluated, and the results were compared with those of an antesternally reconstructed esophagus. These approaches were both used by the same surgical team. An intrathoracic anastomosis using the EEA stapler was made in 53 patients with carcinoma of the thoracic esophagus. Minor anastomotic leakage occurred in five patients (9.4%). Good results were obtained with total parenteral nutrition for 2 weeks. Intrathoracic anastomotic complications were never fatal. Among another 106 patients with antesternally reconstructed esophagus, with the EEA stapler there were 28 patients with anastomotic leakage (26.4%) and two operative mortalities (1.9%). Intrathoracic anastomosis with the EEA stapler is recommended because it is secure and the operative procedure is simple and time-saving. For successful use of the instrument, proper technical procedures must be followed.

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Esophageal carcinoma metastatic to the stomach. A clinicopathologic study of 35 cases

Saito

Iizuka

Kato

et al. 1985

Cancer

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Esophageal carcinoma metastatic to the stomach was analyzed in 35 patients. Ten were discovered in surgical specimens and 25 at autopsy. All patients were men with a mean age of 62 years. Primary lesions were most frequently located in the middle of thoracic esophagus and were larger than 7 cm. Undifferentiated carcinoma was found in 29% of the patients. Local spread of the primary lesions to neighboring structures was seen in 34%. Lymphatic invasion, and intramural metastases within the esophagus, as well as lymph node metastases, were predominant. Metastatic lesions within the stomach were mostly located in the gastric cardia, were less than 2 cm or more than 4 cm in size, and resembled submucosal tumors. Gastric metastases occasionally spread from the submucosa to neighboring structures. In spite of aggressive treatment, the prognosis was extremely poor because of multiple spread of carcinoma to local regions, lymph nodes, and distant organs. The clinicopathologic characteristics of this disease and possible treatment are discussed.

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Carcinoma of the thoracic esophagus

Cited by 25 publications

References 17 publications

Esophageal squamous cell carcinoma: Pathology and prognosis

Esophageal squamous cell carcinoma: Pathology and prognosis

Safety of EEA staplers for anastomosis between upper esophagus and the gastric tube

Esophageal carcinoma metastatic to the stomach. A clinicopathologic study of 35 cases

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