2013
DOI: 10.1007/s00595-013-0612-7
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Carcinosarcoma of the liver: report of a case

Abstract: A 64-year-old Japanese woman without a history of viral hepatitis was admitted for investigation of a huge liver mass. The tumor, measuring 14 × 12 × 22 cm, had invaded the diaphragm, right lung, and inferior vena cava. Serum examinations demonstrated high levels of carbohydrate antigen 19-9 (CA19-9), and the Child-Pugh score was A. She underwent right lobectomy of the liver and partial resection of the right diaphragm, right lung, and inferior vena cava. Radio- and chemotherapy were also given, but she died o… Show more

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Cited by 14 publications
(13 citation statements)
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“…Others argue that primary hepatocellular carcinoma transforms into mesenchymal component; the presence of transitional or transformational zones between carcinoma and sarcoma in some cases supports this view [7][8][9]. According to the study by Yamamoto et al, which analyzed the reports published before 2003, more than half of the liver carcinosarcoma patients had a medical history of chronic viral hepatitis or cirrhosis [2,4], which supports that the opinion of the latter. Although there have been many studies of predictive and prognostic biomarkers in liver cancer (including primary liver cancer and metastatic liver cancer) [10], there are still no prognostic biomarkers studied in liver carcinosarcoma.…”
Section: Discussionmentioning
confidence: 85%
See 1 more Smart Citation
“…Others argue that primary hepatocellular carcinoma transforms into mesenchymal component; the presence of transitional or transformational zones between carcinoma and sarcoma in some cases supports this view [7][8][9]. According to the study by Yamamoto et al, which analyzed the reports published before 2003, more than half of the liver carcinosarcoma patients had a medical history of chronic viral hepatitis or cirrhosis [2,4], which supports that the opinion of the latter. Although there have been many studies of predictive and prognostic biomarkers in liver cancer (including primary liver cancer and metastatic liver cancer) [10], there are still no prognostic biomarkers studied in liver carcinosarcoma.…”
Section: Discussionmentioning
confidence: 85%
“…Even among those patients who can receive surgery resection, most die within 1 year due to the recurrence. The median survival time of patients with metastatic diseases is only about 6 months [4]. Conducting clinical studies in liver carcinosarcoma is very difficult due to the low incidence of this malignancy, and the treatment experiences of such patients from case reports or case series are very important in choosing regimen for patients with advanced diseases.…”
mentioning
confidence: 99%
“…In the retrospective literature, 24 articles 2,3,[7][8][9][10][11]13,14,17,[19][20][21][22][23][24][26][27][28][29][30][31][32][33] were involved in the imaging manifestations, including our study of total of 35 patients. Due to the different proportion of carcinomatous components and sarcomatous components in HCS, and their pathological types were not the same, the imaging manifestations were different.…”
Section: Discussionmentioning
confidence: 99%
“… 2 35 Among them, there were 24 related to image representation. 2 , 3 , 7 11 , 13 , 14 , 17 , 19 24 , 26 33 …”
Section: Methodsmentioning
confidence: 99%
“…Although radical resection is still recommended [ 2 ], the presence of extrahepatic metastases, vessel involvement, and/or invasion of surrounding organs renders curative resection impossible. Careful follow-up and postoperative intervention, including radiotherapy and chemotherapy, might be beneficial for extending disease-free survival [ 4 , 7 , 11 , 18 ].…”
Section: Discussionmentioning
confidence: 99%