Carcinosarcoma of the parotid gland: Report of a case with parapharyngeal presentation

Carcinosarcoma of the Palate

“…CASA has been observed in the floor of the mouth, parotid gland, esophagus, ampulla of Vater, gallbladder, lung, thymus, urinary bladder, prostate, ovary and spleen. [1][2][3][4][5][6][7][8][9] The epithelial component in CASA is usually a squamous cell carcinoma (SCC) that may be inconspicuous or in situ. 4 The sarcomatoid component may be bland, resembling granulation tissue, or pleomorphic and bizarre, resembling osteosarcoma or malignant fibrous histioCytologic recognition and careful interpretation of the malignant mesenchymal and epithelial components are the key to the correct diagnosis, with immunocytochemistry an ancillary tool.…”