This research introduces a novel method for forecasting cardiovascular diseases using an advanced combination of K-means++ clustering, Principal Component Analysis (PCA), and Logistic Regression techniques. Given the global impact of cardiovascular diseases as a primary cause of death, this research utilizes a comprehensive dataset to tackle the prediction challenges associated with CVDs. Initially employing K-means++ for enhanced data quality, followed by PCA for dimensionality reduction, the study applies Logistic Regression for outcome prediction, achieving remarkable accuracy, specificity, and sensitivity. This methodological rigor offers a promising avenue for early and accurate CVDs detection, significantly outperforming traditional predictive models. By refining data through these steps, the study ensures the predictive model is built on a solid foundation, enhancing the reliability and generalizability of the predictions. The integration of these advanced analytical techniques marks a step forward in the pursuit of effective cardiovascular disease management, highlighting the importance of data preprocessing in predictive modeling.