Cardiac Arrhythmias, Snoring, and Sleep Apnea

Hoffstein, V.; Mateika, Susan

doi:10.1378/chest.106.2.466

Cited by 182 publications

(113 citation statements)

References 19 publications

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“…Similar results were observed in a prospective study, where 58% of patients with an AHI .10 events?h -1 , and 82% of patients with mean nocturnal oxygenation ,90%, had supraand ventricular ectopics [71]. In a study including 38 patients with reduced left ventricular ejection fraction treated with a cardioverter-defibrillator, 41% had sleep-related breathing disorders (OSA and Cheyne-Stokes breathing) and VPCs occurred significantly more often during sleep disordered breathing than during normal respiration [93].…”

Section: Ventricular Arrhythmias Observational Studiessupporting

confidence: 87%

“…The prevalence of supraventricular (atrial and sinus) arrhythmias has been estimated to be approximately 50% among patients with severe OSA, compared with about 25% in patients with mild OSA and 20% in control subjects without OSA [71]. In a study looking at patients with newly diagnosed OSA, a prevalence of supraventricular ectopics (SVE) of up to 98%, and SVT of up to 35%, was found [70].…”

Section: Observational Studies Regarding Atrial Arrhythmiasmentioning

confidence: 99%

“…Moreover, patients with OSA were found to have more sinus tachycardia and SVE compared with simple snorers and control subjects without OSA. The number of both nocturnal SVT and SVE has been shown to be significantly higher in patients experiencing nocturnal hypoxia and was related to minimum oxygen saturation during the night [46,71]. In one of these studies the incidence of daytime SVT was correlated with increased nocturnal and diurnal urinary catecholamine excretion, and the number of daytime sinus tachycardia were correlated with apnoea/hypopnoea index (AHI) [46].…”

Section: Observational Studies Regarding Atrial Arrhythmiasmentioning

confidence: 99%

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Effects of obstructive sleep apnoea on heart rhythm

2012

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Symptomatic obstructive sleep apnoea (OSA) has been proven to be a risk factor for hypertension and vascular dysfunction, and has been proposed to be causally related with cardiac arrhythmias and sudden cardiac death.Searches of bibliographical databases revealed that several mechanisms seem to underpin the association between OSA and cardiac arrhythmias: intermittent hypoxia associated with autonomic nervous system activation and increased oxidative stress, which may lead to cardiac cellular damage and alteration in myocardial excitability; recurrent arousals, resulting in sympathetic activation and coronary vasoconstriction; and increased negative intrathoracic pressure which may mechanically stretch the myocardial walls and, thus, promote acute changes in myocardial excitability as well as structural remodelling of the myocardium.Findings from cross-sectional studies suggest a high prevalence of cardiac arrhythmias in patients with OSA and a high prevalence of OSA in those with cardiac arrhythmias. Preliminary evidence from uncontrolled interventional studies suggests that treatment of OSA may prevent cardiac arrhythmias.In conclusion, there is preliminary evidence that OSA is associated with the development of cardiac arrhythmias. Data from randomised controlled studies are needed to definitively clarify the role of OSA in arrhythmogenesis.

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Section: Ventricular Arrhythmias Observational Studiessupporting

confidence: 87%

Section: Observational Studies Regarding Atrial Arrhythmiasmentioning

confidence: 99%

Section: Observational Studies Regarding Atrial Arrhythmiasmentioning

confidence: 99%

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Effects of obstructive sleep apnoea on heart rhythm

2012

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“…Ventricular arrhythmias, primarily premature ventricular contractions, have been reported in up to 66% of patients with sleep apnea, which is significantly higher than the rates reported in persons without sleep apnea (0% to 12%). 226,227 However, there are no conclusive data demonstrating a primary etiologic role for OSA in ventricular arrhythmias.…”

Section: Prevalence Of Arrhythmias In Sleep Apneamentioning

confidence: 99%

Sleep Apnea and Cardiovascular Disease

et al. 2008

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“…In the Wisconsin Sleep Cohort Study and the Sleep Heart Health Study, it was found that there was a relation between OSA and hypertension [11,12]. OSA patients have an increased risk of developing coronary artery disease [13], cerebrovascular disease [14], atherosclerosis [15], arterial stiffness [16], cardiac arrhythmias [17,18] and heart failure [19]. OSA poses important perioperative risks for obese individuals who are particularly vulnerable during anaesthesia and sedation and are at an increased risk of developing postoperative respiratory and cardiopulmonary complications [20,21,22].…”

Section: Introductionmentioning

confidence: 99%

Screening for obstructive sleep apnoea in obesity and diabetes – potential for future approaches

Seetho

Wilding

2013

Eur J Clin Investigation

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Background It is recognised that sleep-disordered breathing (SDB), in particular, obstructive sleep apnoea (OSA) is associated with obesity and diabetes. The complications of OSA include dysregulation of metabolic and cardiovascular homeostasis. With the growing population of diabetes and obesity globally, it is becoming apparent that identifying and screening patients who are at risk is becoming increasingly crucial. Many patients may remain unaware of the potential diagnosis and continue to be undiagnosed. The high prevalence of OSA poses a demanding challenge to healthcare providers in order to provide sufficient resources and facilities for patient diagnosis and treatment.

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Cardiac Arrhythmias, Snoring, and Sleep Apnea

Cited by 182 publications

References 19 publications

Effects of obstructive sleep apnoea on heart rhythm

Effects of obstructive sleep apnoea on heart rhythm

Sleep Apnea and Cardiovascular Disease

Screening for obstructive sleep apnoea in obesity and diabetes – potential for future approaches

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