Cardiac Damage Staging Predicts Outcomes in Aortic Valve Stenosis After Aortic Valve Replacement

Abdelfattah, Omar M.; Jacquemyn, Xander; Sá, Michel Pompeu; Jneid, Hani; Sultan, Ibrahim; Cohen, David J.; Gillam, Linda D.; Aron, Lucy; Clavel, Marie-Annick; Pibarot, Philippe; Bax, Jeroen J.; Kapadia, Samir R.; Leon, Martin; Généreux, Philippe

doi:10.1016/j.jacadv.2024.100959

JACC: Advances

2024

DOI: 10.1016/j.jacadv.2024.100959

|View full text |Cite

Cardiac Damage Staging Predicts Outcomes in Aortic Valve Stenosis After Aortic Valve Replacement

Omar M. Abdelfattah,

Xander Jacquemyn,

Michel Pompeu Sá

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article3

Relationship

Self Cite0

Independent3

Authors

Journals

Cited by 3 publications

References 55 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Aortic Valve Replacement vs Clinical Surveillance in Asymptomatic Severe Aortic Stenosis

Généreux,

Banovic,

Kang

et al. 2024

Journal of the American College of Cardiology

View full text Add to dashboard Cite

Aortic Valve Replacement vs Clinical Surveillance in Asymptomatic Severe Aortic Stenosis

Généreux,

Banovic,

Kang

et al. 2024

Journal of the American College of Cardiology

View full text Add to dashboard Cite

Parsing the Shades of Gray of Myocardial Fibrosis in Aortic Stenosis

Wang,

Dong

2024

JACC: Cardiovascular Imaging

View full text Add to dashboard Cite

Clinical Outcomes According to Aortic Stenosis Management: Insights From Real‐World Practice

Coisne,

Montaigne,

Aghezzaf

et al. 2024

JAHA

View full text Add to dashboard Cite

Background Real‐world data regarding clinical outcomes according to aortic stenosis (AS) management are scarce. Therefore, we aimed to investigate long‐term management across the spectrum of outpatients with AS. Methods and Results Between May 2016 and December 2017, consecutive outpatients with mild (peak aortic velocity, 2.5–2.9 m/s), moderate (3–3.9 m/s), and severe AS (≥4 m/s) were included by 117 cardiologists in the VALVENOR (Follow‐Up of a Cohort of Patients With Valvular Aortic Stenosis in the Nord‐pas‐de‐Calais Region) study and followed‐up for aortic valve replacement (AVR) and modes of death. Among 2704 patients included, 1156 (42.7%) had mild, 1121 (41.5%) moderate, and 427 (15.8%) severe AS. After a median follow‐up of 5 years, 993 AVRs (488 surgical and 505 transcatheter) and 1098 deaths occurred. The 5‐year cumulative incidence of AVR or of the composite of death or AVR was 13.3% and 45.2% in mild AS, 45.5% and 75.3% in moderate AS, and 62.8% and 90.6% in severe AS, respectively. Of the 292 patients who met the criteria for AVR but were not treated, AVR was considered futile in 137 patients and 155 patients refused AVR. Mortality rates after 3 years were high: 86% for anticipated futility and 72.3% for refusal. While patients at anticipated futility showed a well‐balanced proportion of cardiovascular and noncardiovascular deaths, cardiovascular deaths predominated among those who refused AVR. Conclusions At 5‐year follow‐up, only two thirds of patients with severe AS underwent AVR. Patients with untreated severe AS experienced high mortality rates, mostly cardiovascular for patients who declined AVR. This advocates for better patient education based on shared decision making and for optimizing AS quality of care, from diagnosis to treatment.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Cardiac Damage Staging Predicts Outcomes in Aortic Valve Stenosis After Aortic Valve Replacement

Cited by 3 publications

References 55 publications

Aortic Valve Replacement vs Clinical Surveillance in Asymptomatic Severe Aortic Stenosis

Aortic Valve Replacement vs Clinical Surveillance in Asymptomatic Severe Aortic Stenosis

Parsing the Shades of Gray of Myocardial Fibrosis in Aortic Stenosis

Clinical Outcomes According to Aortic Stenosis Management: Insights From Real‐World Practice

Contact Info

Product

Resources

About