Cardiac fibroma

Yamaguchi, Masahiro; Hosokawa, Y; Ohashi, H; Imai, Masatake; Oshima, Yoshihiro; Minamiji, Katsumi

doi:10.1016/s0022-5223(19)35076-7

Cited by 31 publications

(2 citation statements)

References 22 publications

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“…Primary cardiac tumours are quite uncommon. Even less prevalent are cardiac tumours in perinatal autopsy with an incidence of 0.0017% to 0.28% 1–3. Most benign cardiac tumours are cardiac rhabdomyomas, which are frequently diagnosed antenatally by echocardiography 4.…”

Section: Introductionmentioning

confidence: 99%

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Cardiac fibroma presenting as hypoplastic left heart syndrome in a foetus: causal or coincidental?

Sundari,

Gurusamy

2024

BMJ Case Rep

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Primary cardiac tumours are very rare. Cardiac tumours in the perinatal period are even more uncommon with a prevalence of 0.0017% to 0.28% in autopsy series. The majority of benign cardiac tumours are cardiac rhabdomyomas, followed by cardiac fibromas. Another rare congenital heart disease is hypoplastic left heart syndrome (HLHS). Here we present a 21-week-old foetus diagnosed antenatally with HLHS on foetal echocardiogram. An autopsy done on the foetus following medical termination of pregnancy revealed a cardiac fibroma in the ventricular septum. It is very uncommon to have a combination of two congenital heart diseases. An extensive literature review revealed only three cases that had rhabdomyoma and associated HLHS. This case presented with cardiac fibroma which in early gestation would have resulted in left ventricular outflow obstruction leading to the development of HLHS. Small cardiac tumours which are difficult to detect by echocardiogram in early gestation can lead to the development of HLHS. A thorough and hierarchical autopsy examination of such cases can help in a better understanding of the relationship between HLHS and cardiac tumours.

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Section: Introductionmentioning

confidence: 99%

“…It typically originates as a solitary intratumoral lesion from the ventricular septum or ventricular free wall. Although cardiac fibroma is a benign tumour that does not metastasise or infiltrate, it can cause conductive or haemodynamic abnormalities secondary to obstruction resulting in sudden death 1…”

Section: Introductionmentioning

confidence: 99%