Cardiac Function in Chronic Renal Failure Before and After Hemodialysis

Strangfeld, D; Günther, K; Böhm, R.; Günther, H; Buchali, K; Dutz, H

doi:10.1159/000169623

Cited by 16 publications

(6 citation statements)

References 4 publications

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“…The study performed by Strangfeld et at. [7] on 14 adult patients indicated that the hemodialysis did not alter cardiac output, stroke volume or left ventricular work. The study showed that a decrease in heart chamber volume in the face of constant total blood volume took place fol lowing a reduction of extracellular fluid indicated by weight loss.…”

Section: Discussionmentioning

confidence: 96%

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Effects of Hemodialysis on Myocardial Function in Pediatric Patients

O’Regan

Villemand

Revillon

et al. 1980

Nephron

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The effect of hemodialysis on myocardial function in 10 pediatric chronic hemodialysis patients was assessed utilizing echocardiography. Parameters of cardiac function were measured prior to and immediately after dialysis. A significant decrease in cardiac output was observed post-dialysis. Unlike that observed in adult patients a real improvement in myocardial function as indicated by an increase in the mean velocity of circumferential fibre shortening was evident post-dialysis.

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Section: Discussionmentioning

confidence: 96%

“…Previous studies assessing effects of hemodialysis on myocardial function have all been done on adult patients [6][7][8][9][10]. Thus, the effects of possible accelerated arterio sclerosis on myocardial performance in these patients might have obscured any true improvement induced by efficient dialysis.…”

Section: Discussionmentioning

confidence: 99%

Effects of Hemodialysis on Myocardial Function in Pediatric Patients

O’Regan

Villemand

Revillon

et al. 1980

Nephron

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“…Cardiac output fell after dialysis, and there was a further fall after tilt. Previous studies suggest that cardiac output may fall [29,30] or remain unchanged [31] in response to haemo dialysis. In normal man assumption of an upright posture is associated with a fall of up to 25% in cardiac output [32], The fall in cardiac output in our patients is unlikely to be due to a reduction in afterload [33], since calculated peripheral vascular resistance was increased by dialysis, but the decrease in stroke volume is partly compensated for by an increase in heart rate.…”

Section: Discussionmentioning

confidence: 99%

Effect of Haemodialysis on the Control of the Circulation in Patients with Chronic Renal Failure

1985

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The mechanisms of hypotension during haemodialysis were investigated by studying cardiovascular reflexes, body fluid volumes, and osmolality in 11 patients with renal failure before and after haemodialysis and in 17 normal subjects before and after furosemide diuresis. Blood pressure and heart rate responses to tests of autonomic nervous function were unaffected in either group except that in the patients, head-up tilt after haemodialysis caused a fall in blood pressure. This was associated with a greater fall in cardiac output than before haemodialysis but with a similar rise in peripheral vascular resistance. Resting plasma noradrenaline levels were higher than normal, and the rise in plasma noradrenaline levels in response to tilt was unaffected by haemodialysis. Plasma renin activity rose in response to head-up tilt in normal subjects, but not in patients either before or after haemodialysis. Our studies indicate that changes in plasma potassium and osmolality or the possible peripheral circulatory effects of acetate do not impair the regulation of the circulation in response to haemodialysis. Haemodialysis does not reduce plasma noradrenaline levels. Impaired myocardial function in response to fluid depletion or unresponsiveness of the renin-angiotensin system may contribute to haemodialysis hypotension.

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“…Although hemodynamic changes associated with hemodialysis in pa tients with chronic renal failure have already been reported by Del G reco et al [6], Hampers et al [10], and others [5,11,22], most previous investigations have been confined to comparisons of the status before and after hemodialysis. In this study, the accent was placed on hemodynamic alterations during hemodialysis as induced by increasing the extracor poreal blood flow rate in a stepwise fashion from 100 to 400 ml/min.…”

Section: Discussionmentioning

confidence: 99%

Hemodynamic Changes during Hemodialysis

et al. 1978

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35 patients with chronic renal failure were examined during the first 2 h of hemodialysis by invasive and non-invasive methods. The cardiac output was determined by the dye dilution technique in 11 of these patients and by Swan-Ganz catheterization in 5. In the patients without severe myocardial damage, the cardiac output during hemodialysis showed a significant increase (p < 0.05), accompanied by a significant decrease of both mean blood pressure (p < 0.05) and total peripheral resistance (p < 0.05). Mean pulmonary artery pressure and pulmonary artery wedge pressure were reduced in all cases during hemodialysis. The increase in cardiac output during hemodialysis in patients with chronic renal failure may be attributed to the decrease in afterload.

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Cardiac Function in Chronic Renal Failure Before and After Hemodialysis

Cited by 16 publications

References 4 publications

Effects of Hemodialysis on Myocardial Function in Pediatric Patients

Effects of Hemodialysis on Myocardial Function in Pediatric Patients

Effect of Haemodialysis on the Control of the Circulation in Patients with Chronic Renal Failure

Hemodynamic Changes during Hemodialysis

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