2024
DOI: 10.3390/children11020208
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Cardiac Implications of Adenotonsillar Hypertrophy and Obstructive Sleep Apnea in Pediatric Patients: A Comprehensive Systematic Review

Marco Zaffanello,
Refika Hamutcu Ersu,
Luana Nosetti
et al.

Abstract: This review investigates the relationship between pediatric obstructive sleep apnea, often associated with adenotonsillar hypertrophy, and cardiovascular health, particularly pulmonary hypertension. We conducted a comprehensive literature search using electronic databases, including Medline Pub-Med, Scopus, and the Web of Science. The study analyzed a total of 230 articles and screened 48 articles, with 20 included in the final analysis, involving 2429 children. The PRISMA flowchart visually illustrates the se… Show more

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“…2 Sleep-disordered breathing (SDB) can lead to significant health issues in both children and adults [1][2][3]. SDB is linked to a variety of detrimental effects, including intermittent hypoxia, oxidative stress, sleep fragmentation, high blood pressure, and heart disease [4][5][6][7].…”
Section: Introductionmentioning
confidence: 99%
“…2 Sleep-disordered breathing (SDB) can lead to significant health issues in both children and adults [1][2][3]. SDB is linked to a variety of detrimental effects, including intermittent hypoxia, oxidative stress, sleep fragmentation, high blood pressure, and heart disease [4][5][6][7].…”
Section: Introductionmentioning
confidence: 99%