Cardiac lipoma

Ismail, Imtiaz; Al-Khafaji, Khalid; Mutyala, Monica; Aggarwal, Saurabh; Cotter, William M.; Hakim, Hosam; Khosla, Sandeep; Arora, Rohit

doi:10.3402/jchimp.v5.28449

Cited by 27 publications

(24 citation statements)

References 8 publications

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“…They can occur in any age group, but are most prevalent between ages 40–60 years [3]. They are usually asymptomatic and hence remain undetected or are discovered incidentally.…”

Section: Discussionmentioning

confidence: 99%

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Invasive Cardiac Lipoma: a case report and review of literature

D’Souza

Shah²,

Abbass

et al. 2017

BMC Cardiovasc Disord

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BackgroundCardiac lipomas are rare benign tumors of the heart. They are usually asymptomatic and are thus most often diagnosed on autopsies. Symptoms, when present, depend upon the location within the heart. Typical locations are the endocardium of the right atrium and the left ventricle. Diagnostic modality of choice is cardiac MRI. Treatment guidelines have not yet been established due to the very low prevalence of these tumors and are thus guided by the patient’s symptomatology.Case presentationWe describe a case of an invasive cardiac lipoma, wherein the initial symptom of the patient was shortness of breath. Although the echocardiogram visualized the tumor in the right atrium, a cardiac MRI was performed for better tissue characterization. The MRI revealed a large, fat containing, septated mass in the right atrium with invasion into the inter-atrial septum and inferior cavoatrial junction. There was also invasion of the coronary sinus along the inferior and left lateral aspect of the posterior atrioventricular groove. Although the mass appeared to represent a lipoma by imaging characteristics, the unusual extension into the coronary sinus led to consideration of a low-grade liposarcoma in the differential. Thus a pre-operative biopsy was performed along with MDM2 gene amplification to rule out a liposarcoma preceding surgical excision.ConclusionCardiac lipomas are well-characterized on cardiac MRI, which is the diagnostic modality of choice. Typical locations are the right atrium and the left ventricle. However, in those with atypical features such as invasion of the coronary sinus, pre-operative biopsy for histopathologic confirmation is imperative to exclude well-differentiated liposarcoma. Our patient with a simple lipoma underwent partial resection to relieve symptoms. We discuss prognosis and treatment of symptomatic cardiac lipomas.

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“…They can occur in any age group, but are most prevalent between ages 40–60 years [3]. They are usually asymptomatic and hence remain undetected or are discovered incidentally.…”

Section: Discussionmentioning

confidence: 99%

“…They originate from the subendocardium (50%), subepicardium (25%) or myocardium (25%) and are of varying sizes. Typical locations include the right atrium and the left ventricle [3]. Distinction from lipomatous hypertrophy of the myocardium on imaging can be difficult.…”

Section: Introductionmentioning

confidence: 99%

Invasive Cardiac Lipoma: a case report and review of literature

D’Souza

Shah²,

Abbass

et al. 2017

BMC Cardiovasc Disord

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“…Hemangiomas are benign tumors that may rarely develop in the cardiac region . Pericardial involvement is even more rare (Figure ) …”

Section: Cardiac/pericardial Hemangioma Clinical Presentationmentioning

confidence: 99%

“…1 Pericardial involvement is even more rare ( Figure 1). [1][2][3][4][5][6][7] We present a case of a primary pericardial hemangioma in which three-dimensional transesophageal echocardiography (3DTEE) provided additional information over two-dimensional transesophageal echocardiography (2DTEE) that helped in making a confident diagnosis of hemangioma by demonstration of characteristic 3D echocardiographic findings. We also summarize in a tabular form the clinical presentation, diagnostic features, prognosis, and management of cardiac/pericardial hemangiomas as well as all the reported cases that have been described in the literature so far using 3D echocardiography (Tables 1-5).…”

Section: Introductionmentioning

confidence: 99%

Incremental benefit of three‐dimensional transesophageal echocardiography in the assessment of a primary pericardial hemangioma

et al. 2017

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Hemangiomas are rarely found in the heart and pericardial involvement is even more rare. We report a case of primary pericardial hemangioma, in which three-dimensional transesophageal echocardiography (3DTEE) provided incremental benefit over standard two-dimensional images. Our case also highlights the importance of systematic cropping of the 3D datasets in making a diagnosis of pericardial hemangioma with a greater degree of certainty. In addition, we also provide a literature review of the features of cardiac/pericardial hemangiomas in a tabular form.

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“…Intramuscular lipomas are rare and characterized due to its nature of in ltrating into muscle bres [22]. Cardiac lipomas constitute 8.4% of primary heart and pericardial tumours and intracavitary lesions can cause dyspnoea, syncope, atrial brillation and angina [2,23,24]. Intracranial lipomas constitute 0.1-0.5% of all primary brain tumours [2].…”

Section: Introductionmentioning

confidence: 99%

Surgical excision of complex lipoma from the foot: a case report 

Uddin

Flanagan

Reilly

2020

Preprint

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Background: Soft tissue malignant tumours of the foot and ankle are rare. Diagnostic imaging and interventional biopsy are vital to establish the nature and grading of a suspicious tumour prior to surgical intervention. The purpose of the study is to provide an account on how a symptomatic mass to the plantar aspect of the foot warranted a referral to a sarcoma centre, highlighting the importance of having urgent access to diagnostic imaging and a pathway to refer suspected cases to specialist centres. Method: A single patient with a symptomatic soft tissue tumour of the plantar foot was referred from our service to the regional sarcoma centre. It was considered to be benign and therefore open surgical resection was performed under local anaesthesia by our team, and the lesion sent for histopathological examination. Results: Histopathological analysis identified the excised mass as a lipoma to show no atypia or necrosis and mature adipose tissue with fibrous bands. At 2 years postoperatively there was no recurrence and the patient presented an asymptomatic foot. Favourable patient reported outcomes measures were observed. Conclusion: United Kingdom (UK) Guidelines suggest that all soft tissue masses of suspicious nature, greater than 50mm, deep seated irrespective of size, or fast growing should be referred to a sarcoma unit prior to surgical management. European guidance identifies a threshold of 15mm for a mass in the foot. Patients presenting with red flag symptoms irrespective of size of mass should be referred to a sarcoma centre. Advanced imaging and multidisciplinary input to enable appropriate surgical planning is recommended for these soft tissue tumours that present to the foot and ankle surgeon. Level of evidence: V case study.

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Cardiac lipoma

Cited by 27 publications

References 8 publications

Invasive Cardiac Lipoma: a case report and review of literature

Invasive Cardiac Lipoma: a case report and review of literature

Incremental benefit of three‐dimensional transesophageal echocardiography in the assessment of a primary pericardial hemangioma

Surgical excision of complex lipoma from the foot: a case report

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Cardiac lipoma

Cited by 27 publications

References 8 publications

Invasive Cardiac Lipoma: a case report and review of literature

Invasive Cardiac Lipoma: a case report and review of literature

Incremental benefit of three‐dimensional transesophageal echocardiography in the assessment of a primary pericardial hemangioma

Surgical excision of complex lipoma from the foot: a case report&nbsp;

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Surgical excision of complex lipoma from the foot: a case report