Cardiac Metastasis in a Living Patient With Laryngeal Squamous Cell Carcinoma

Tregubenko, Polina; White, Sherrie; Zvonarev, Valeriy; Kumar, Abhishek

doi:10.7759/cureus.16214

Cited by 2 publications

(1 citation statement)

References 26 publications

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“…Tregubenko P et al [25] 2021 1 63/M RV LSCC 4.6X3.6 Palliative radiotherapy 0.5/Death Mahalwar G et al [26] 2022 1 29/M RV TGCT 7.4X6.0 Do-not-resuscitate comfort care 0/Death Goldberg AB et al [27] 2019 1 56/F RA Chondrosarcoma 5.8X2.9 Surgery Unknown Tian L et al [28] 2022…”

Section: Unknownmentioning

confidence: 99%

Diagnosis and treatment of right ventricular metastasis from esophageal squamous cell carcinoma: An unusual case report and a literature review

Luo,

Luo

2023

Medicine

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Background: Right ventricular metastasis from esophageal squamous cell carcinoma is very rare and only seen in few case reports. Patients with cardiac metastasis have a poor prognosis with a median survival period of 4 weeks due to the lack of standardized and effective treatment guidelines. Therefore, we aimed to clarify the feature and treatment of cardiac metastasis through literature review and reporting of an unusual case. Case: We reported a case of a 67 years-old man diagnosed as right ventricular metastasis from esophageal squamous cell with the help of echocardiography and pathological biopsy. Moreover, the patient survival period reached an astonishing 6 months, which far exceeded 4 weeks reported in previous literature. Methods: We searched for relevant literature in the past decade on PUBMED and summarized the content of the literature to better clarify cardiac metastasis. Conclusion: Cardiac metastatic likely to occur in the elderly and in the right side of heart which related to hemodynamics. Surgical resection of metastatic tumors is the main treatment method, but patients usually die during the perioperative period due to its complexity and difficulty. Meanwhile, we have proposed some potentially effective treatment measures.

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Section: Unknownmentioning

confidence: 99%

Diagnosis and treatment of right ventricular metastasis from esophageal squamous cell carcinoma: An unusual case report and a literature review

Luo,

Luo

2023

Medicine

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Distant Multilevel Spinal Metastasis Secondary to Hypopharyngeal Squamous Cell Carcinoma

Kirby,

Kim,

Abdurrahman

et al. 2024

Cureus

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Head and neck squamous cell carcinomas account for most head and neck malignancies. While multimodality treatment may be offered for locally advanced cancer, distant metastasis still occurs in a significant number of patients. This paper aims to present a rare case of a patient who developed bony metastases in the cervical spine from a primary hypopharyngeal malignancy status post-laryngopharyngectomy.We report a case of a male patient presenting with acute-on-chronic hypercapnic and hypoxic respiratory failure with two months of dysphagia and weight loss. On arrival, a barium swallow revealed mucosal irregularity of the upper thoracic esophagus as well as narrowing and stenosis. A direct laryngoscopy with biopsy revealed squamous cell carcinoma of the hypopharynx. CT neck and chest were obtained for staging. He underwent a total laryngopharyngectomy, bilateral neck dissections, and a free flap. His final staging was pT4aN2c cM0. Three months post-admission, during inpatient radiation therapy, the patient reported midline neck pain with focal bone tenderness, and an MRI was obtained of his cervical and thoracic spine with a report concerning spinal metastasis. A subsequent bone biopsy showed findings consistent with osseous metastasis from a primary hypopharyngeal squamous cell carcinoma. After multidisciplinary goals of care discussions, the patient ultimately decided to be discharged to inpatient hospice. This report highlights a rare case of hypopharyngeal carcinoma metastasis to the cervical spine. Despite its rarity and poor prognosis, such a metastasis should be considered in the differential diagnosis of patients with a history of hypopharyngeal squamous cell carcinoma and localizing symptoms.

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Cardiac Metastasis in a Living Patient With Laryngeal Squamous Cell Carcinoma

Cited by 2 publications

References 26 publications

Diagnosis and treatment of right ventricular metastasis from esophageal squamous cell carcinoma: An unusual case report and a literature review

Diagnosis and treatment of right ventricular metastasis from esophageal squamous cell carcinoma: An unusual case report and a literature review

Distant Multilevel Spinal Metastasis Secondary to Hypopharyngeal Squamous Cell Carcinoma

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