Cardiac Musculature of the Intrapulmonary Vein in the Musk Shrew.

Endo, Hideki; Kurohmaru, Masamichi; Nishida, Takao; Hattori, Satoshi; Hayashi, Yoshihiro

doi:10.1292/jvms.54.119

Cited by 13 publications

(9 citation statements)

References 15 publications

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“…The occurrence of the cardiac muscle in the wall of the pulmonary vein has been reported in various species (BENNINGHOFF, 1930;TAKINO, 1933;LUDATSCHER, 1968;ENDO et al, 1992). Previous studies have macroscopically and histologically demonstrated in several kinds of animals and human that the cardiac muscle is also present in the wall of the venae cavae adjacent to the heart (PAPEZ, 1920;HUSTEN, 1926;BENNINGHOFF, 1930;GLOMSET and GLOMSET, 1940;KARRER, 1959;THOMAS, 1959;CARROW and CALHOUN, 1964;NATHAN and ELIAKIM, 1966;NATHAN and GLOOBE, 1970;SPACH et al, 1972ENDO et al, 1994).…”

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confidence: 97%

A Histological Study of the Cardiac Muscle of the Human Superior and Inferior Venae Cavae.

Hashizume

Ushiki

Abe

1995

Arch. Histol. Cytol.

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A Histological Study of the Cardiac Muscle of the Human Superior and Inferior Venae Cavae.

Hashizume

Ushiki

Abe

1995

Arch. Histol. Cytol.

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“…While Stieda (1877) and Favaro (1910) reported the existence of cardiac-like musculature in the intrapulmonary vein of moles, we examined that of the musk shrew in detail and suggested that the phylogenetic origin of the structure may be traced back to an insectivore (Endo et al, 1992a). The data of long-clawed shrew supported this suggestion.…”

Section: Discussionmentioning

confidence: 50%

“…The cardiac-like musculature of the pulmonary vein in the common tree shrew may be worth examining morphologically to evaluate evolution of this structure from insectivore to primate. Fortunately, as some species of insectivores were found to possess cardiac-like muscles in the intrapulmonary vein (Stieda, 1877;Favaro, 1910;Endo et al, 1992a), the evolutionary origin of the structure is suggested to trace back to the most primitive mammalian type.…”

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confidence: 99%

Cardiac-like musculature of the intrapulmonary venous wall of the long-clawed shrew (Sorex unguiculatus), common tree shrew (Tupaia glis) and common marmoset (Callithrix jacchus)

et al. 1997

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Background The cardiac‐like musculature is distributed not only in the heart wall but also in the intrapulmonary venous wall in a few species of insectivores. It has been suggested that the evolutionary origin of venous cardiac‐like musculature may be traceable to a basic stock of certain mammalian lines of descent. So, it is important to clarify whether the musculature may be a common structure in lower mammals from insectivores to primates and to examine the functional significance of the structure. Methods The distribution of cardiac‐like musculature in the intrapulmonary venous wall of the long‐clawed shrew (Sorex unguiculatus), common tree shrew (Tupaia glis), and common marmoset (Callithrix jacchus) was observed by light and electron microscopy. The presence of atrial natriuretic polypeptide (ANP) was examined in the musculature by immunohistochemistry. Results All three species contained cardiac‐like myocytes in the tunica media of intrapulmonary venous wall. In the common tree shrew and the common marmoset, cardiac‐like musculature was found in the small intrapulmonary vein of 150–200 μm in diameter, while, in the long‐clawed shrew, it was distributed even in the intrapulmonary vein of 30 μm in diameter. Ultrastructure of myocytes was fundamentally similar to that of atrial myocytes in the long‐clawed shrew and the common tree shrew. The presence of atrial natriuretic polypeptide (ANP) was also demonstrated by immunohistochemistry in the intrapulmonary venous walls of common tree shrews. Conclusions The results indicate that the pulmonary venous cardiac‐like musculature occurs in the lower eutherian mammals from insectivores to primitive primates. The musculature is thought to act as a regulatory pump in pulmonary circulation and as an endocrine apparatus of ANP. Anat. Rec. 247:46–52 © 1997 Wiley‐Liss, Inc.

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“…While functional differences in components of the airway are recognized among different species, it is difficult to estimate the essential roles played by AQP subfamily members in these tissues. In order to understand common functionalities of AQP subfamily members in the respiratory system, more reliable information on these subfamily members is needed.The musk shrew (Suncus murinus) is a small animal that has attracted interest as an experimental insectivorous mammal and exhibits several primitive mammalian characteristics [11,22,47]. The musk shrew shares several similarities with humans in its morphological, physiological, and genetic features [17,20,22,23] and is considered one available model for the study of human physiology and pathology [23,53].…”

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“…The musk shrew (Suncus murinus) is a small animal that has attracted interest as an experimental insectivorous mammal and exhibits several primitive mammalian characteristics [11,22,47]. The musk shrew shares several similarities with humans in its morphological, physiological, and genetic features [17,20,22,23] and is considered one available model for the study of human physiology and pathology [23,53].…”

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Localization of Aquaporin Water Channels in the Airway of the Musk Shrew (Suncus murinus) and the Rat

Maeda

Ito

Tanaka

et al. 2005

The Journal of Veterinary Medical Science

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ABSTRACT. Aquaporins (AQPs) constitute a family of water channels that facilitate membrane water permeability in various tissues of animals. In this study, we compared the expression and localization of AQPs in the respiratory system of the musk shrew (Suncus murinus), which is an insectivore, and the rat by immunohistochemical methods. In both the musk shrew and the rat, AQP1 was expressed throughout the airway in endothelial cells of subepithelial blood vessels and in nasal submucosal fibroblasts. AQP3 and AQP4 were detected in neither the epithelium nor the subepithelial layer of the musk shrew airway, but were abundant in the rat airway epithelium. Musk shrew AQP5 was distributed in the superficial epithelial cells facing the airspaces and in submucosal glandular cells, but, unlike in the rat, not in lung alveolar cells. Additionally, the expression patterns of AQP4 and AQP5 of the musk shrew were partly similar to those of the human previously reported, absence of AQP4 and presence of AQP5 in the upper airway. The expression differences of AQPs between species in the airway indicate that the physiological importance of each AQP may be different in each species. KEY WORDS: aquaporin, lung, nasal mucosa, trachea, water channel.J. Vet. Med. Sci. 67(10): 975-984, 2005 Aquaporins (AQPs) are water-selective channels that increase plasma membrane water permeability in secretory and adsorptive cells that require rapid or regulated water movement [42,43]. In mammals, at least eleven subtypes of AQPs have been identified (AQP0-10) and divided into two groups depending on their sequence homology and functions. Every AQP selectively transports water, but AQP3, -7, and -9 are also permeable with respect to neutral solutes such as urea and glycerol [55].Several AQPs are also expressed in the respiratory system, specifically the nasal mucosa, trachea, bronchus, and lung. AQP1 is the first aquaporin that was identified in the lung of rat [16], and revealed to be localized predominantly to the blood microvascular endothelia adjacent to the airway, alveoli, and pleura [12,13,25,38,39,46,48]. AQP3 was found to be expressed in the basal cells of nasopharynx and trachea epithelia in both rat and human [14,25,28,40]. Expression of AQP4 has been reported in the basolateral membrane of columnar cells of rat nasal, tracheal, and bronchial epithelia [14,40], but not in the human airway [28]. AQP5, which was cloned from rat salivary gland [30,44], has been identified in rat and human lung [26,28,40,44], and AQP5 protein was seen to be localized in lung type 1 pneumocytes of rodents [40], whereas human AQP5 was distributed in the superficial epithelium of the upper airway [28]. However, most of these reports showed transcription levels of AQPs and/or protein localization within a small portion of the airway, and immunohistochemical localization of AQPs throughout the airway has only been reported once in the rat [40] and once in the human [28].In the respiratory system, at least, there are many differences in the localization of AQ...

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Cardiac Musculature of the Intrapulmonary Vein in the Musk Shrew.

Cited by 13 publications

References 15 publications

A Histological Study of the Cardiac Muscle of the Human Superior and Inferior Venae Cavae.

A Histological Study of the Cardiac Muscle of the Human Superior and Inferior Venae Cavae.

Cardiac-like musculature of the intrapulmonary venous wall of the long-clawed shrew (Sorex unguiculatus), common tree shrew (Tupaia glis) and common marmoset (Callithrix jacchus)

Localization of Aquaporin Water Channels in the Airway of the Musk Shrew (Suncus murinus) and the Rat

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