Cardiac Outcomes of Multisystem Inflammatory Syndrome in Children

Abstract

This comprehensive review aims to enhance the clinical management of cardiovascular complications associated with multisystem inflammatory syndrome in children (MIS-C) through a rigorous examination of existing literature. MIS-C frequently affects the cardiovascular system, resulting in a range of manifestations and degrees of severity. Ventricular dysfunction is the most prevalent symptom, while coronary arterial aneurysms are less common compared to Kawasaki disease. Conduction abnormalities are also widely observed, while life-threatening arrhythmias remain relatively rare. Effective management of cardiovascular complications relies on timely supportive care and well-judged immunomodulatory therapy. Given the substantial impact of MIS-C as an acquired heart disease in the pediatric population, the necessity for thorough cardiac assessment and conscientious management cannot be overemphasized in the quest for optimal patient care.