Cardiac output estimation based on arterial and venous blood gas analysis: proposal of a monitoring method

Giraldo-Gutiérrez, D.S.; Gutiérrez, Juan José Velásquez; Ruiz-Villa, Joaquín Octavio

doi:10.5114/ait.2021.105730

Cited by 3 publications

(1 citation statement)

References 21 publications

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“…Arterial blood gas analysis is a technical detection process for the analysis of different types of acid and basic substances in the blood (22) , to explore the changes and speci c conditions at the timing of in ammation peak after surgery. Blood gas analysis is one of the means to assessing the patients' immediate condition at an early clinical stage (23) .…”

Section: Discussionmentioning

confidence: 99%

Tetramethylpyrazine ameliorated sepsis-induced disseminated intravascular coagulation dysfunction and inflammation in rat

zhu,

zhang,

zhou

et al. 2024

Preprint

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Objectives: Objectives: To investigate the protective effect of tetramethylpyrazine (TMP) against the disseminated intravascular coagulation (DIC) dysfunction and inflammation in the rat models infected with sepsis. Methods: Based on a clinical retrospective analysis with sepsis patients, multi-time point, dynamic monitoring and continuous measurement of CECs count, vWF activity, tPA, PAI-1, TXB2, and 6-K-PGF1α of the blood aggregative indicators were designed and employed during experimental period. The arterial blood gas, plasma inflammation levels and global coagulation in septic rat were measured at 24 h after the CLP operation. Results: Clinical sepsis patients on concomitant TMP medication had improved blood counts and coagulation parameters. The levels of the CECs count were significantly increased at about 7 h after the CLP operation injury, and reached a peak value at 24 h and sustained with a steady equilibrium level. The vWF activity, PAI-1, and TXB2/6-K-PGF1α had a marked increase after injury, whereas these indexes were significantly diminished after TMP intervention. At 24 h after CLP operation, the pH, pCO2, sO2, Glu, and Lac was decreased, in contrast the pO2, and HCO3- was increased in septic rats. The levels of IL-1β, IL-6, TNF-α and TF were remarkably up-regulated in the sepsis-induced DIC rats suffering the CLP surgery, and these levels were respectively down-regulated 38%, 45%, 29%, 127% with the TMP intra-peritoneal injection. Conclusions: TMP could effectively improve the coagulation function and reduce the inflammatory response, which had a clear benefit and good outcome for sepsis-induced DIC.

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Section: Discussionmentioning

confidence: 99%

Tetramethylpyrazine ameliorated sepsis-induced disseminated intravascular coagulation dysfunction and inflammation in rat

zhu,

zhang,

zhou

et al. 2024

Preprint

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Comparison between invasive cardiac output and left ventricular assist device flow parameter

Segev,

Copeland,

Sokolski

et al. 2024

European Journal of Cardio-Thoracic Surgery

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OBJECTIVES Evaluate the correlation between left ventricular assist device flow parameter and invasive cardiac output measurements. METHODS We retrospectively evaluated right heart catheterization examinations performed in left ventricular assist device patients from 2 tertiary medical centers. We evaluated the correlation between cardiac output measurement methods (indirect Fick and thermodilution) and pump flow parameter using linear regression, agreement was graphically displayed using Bland-Altman plot technique. Clinical, echocardiographic, pump and haemodynamic parameters were compared between patients with and without discordance, defined as at least 20% difference between measurements. RESULTS The study population consisted of 102 patients (median age 58 [51–64], 86% males, 17 ± 12 months post left ventricular assist device implantation) with a total of 544 measurement compared. Discordance between measurements were present in 102 of 226 (45%) comparisons between indirect Fick and pump flow and in 72 of 161 (48%) between thermodilution and pump flow. A comparison of indirect Fick and left ventricular assist device exhibited a statistical correlation of R = 0.751, and that of thermodilution and left ventricular assist device of R = 0.789. Parameters associated with the presence of discordance between cardiac output measurements included a higher rate of aortic valve opening, lower indirect Fick and higher thermodilution cardiac output. After excluding the lowest tertile of indirect Fick cardiac output values, the correlation between measurements improved (thermodilution: R = 0.879 and indirect Fick: R = 0.843, p < 0.001). CONCLUSIONS The current left ventricular assist device flow parameter provides an estimation of cardiac output that correlates well with indirect Fick and exhibits the strongest correlation with thermodilution. This correlation was stronger after excluding lower cardiac output values.

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Effect of Carbohydrate-Enriched Drink Compared to Fasting on Hemodynamics in Healthy Volunteers. A Randomized Trial

Kukliński

Steckiewicz

Piwowarczyk

et al. 2022

JCM

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Fasting prior to surgery can cause dehydration and alter hemodynamics. This study aimed to determine the impact of a carbohydrate-enriched drink (NutriciaTM Pre-op®) on selected hemodynamical parameters, measured in a non-invasive manner. We enrolled 100 healthy volunteers and measured their weight, height, systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), thoracic fluid content (TFC), thoracic fluid index (TFCI), stroke volume (SV), stroke volume variation (SVV), stroke index (SI), cardiac output (CO), cardiac index (CI), heather index (HI), systolic time ration (STR), systemic time ratio index (STRI), systemic vascular resistance (SVR), and systemic vascular resistance index (SVRI) by a Niccomo™ device, implementing the impedance cardiography (ICG) method. Measurements were performed at the beginning of the study, and after 10 h and 12 h. We randomly allocated participants to the control group and the pre-op group. The pre-op group received 400 mL of Nutricia™ preOp®, as suggested in the ERAS guidelines, within 10 h of the study. Student’s t-test or the Mann–Whitney U test were used to compare the two groups, and p < 0.05 was considered significant. We did not observe any changes in hemodynamical parameters, blood pressure, and heart rate between the groups. We have proven that carbohydrate-enriched drink administration did not have a significant impact on the hemodynamical parameters of healthy volunteers.

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Cardiac output estimation based on arterial and venous blood gas analysis: proposal of a monitoring method

Cited by 3 publications

References 21 publications

Tetramethylpyrazine ameliorated sepsis-induced disseminated intravascular coagulation dysfunction and inflammation in rat

Tetramethylpyrazine ameliorated sepsis-induced disseminated intravascular coagulation dysfunction and inflammation in rat

Comparison between invasive cardiac output and left ventricular assist device flow parameter

Effect of Carbohydrate-Enriched Drink Compared to Fasting on Hemodynamics in Healthy Volunteers. A Randomized Trial

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