See article by Oosenbrug et al., pages 1316e1324 of this issue.Cardiovascular disease remains the leading cause of death in North America with a higher rate of morbidity and mortality in women than in men. 1 After an acute coronary syndrome (ACS), women are more likely than men to die, particularly women younger than the age of 55 years who present with an ST-elevation myocardial infarction. 2,3 Further, women with an ACS suffer from delays in diagnosis and treatment, 4 undergo less invasive management, 5,6 receive less medical therapy, 7 and have higher complication rates such as bleeding, than do men. 8,9 Finally, women have lower socioeconomic status, quality of life, and exercise capacity than their male counterparts. 10 Cardiac rehabilitation (CR) is an outpatient chronic disease management program that encompasses patient education, dietary advice, structured and supervised exercise training, and risk factor assessment and modification after a cardiac event. There are >200 CR rehabilitation programs in Canada; 3 of which also offer women-only programs. 11 Research suggests there are many benefits to CR including reduced morbidity and mortality, improved functional status, improved quality of life, and cost savings for society and the economy. [12][13][14][15] The benefits appear similar in men and women, with some studies suggesting greater mortality reduction in women compared with men, particularly in those with good program adherence. 16 Unfortunately, despite the well known benefits of CR, enrollment rates are low, particularly in women. 17,18 In this issue, Oosenbrug et al. 19 performed a meta-analysis on CR adherence in men and women and quantitatively assessed sex differences in adherence. The mean age was 61 years and women accounted for only 27.3% of participants. The mean duration of CR programs was 15 weeks with a mean frequency of sessions of 2.5 per week. Overall, the mean