2018
DOI: 10.1002/uog.17516
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Cardiac remodeling and pre‐eclampsia: an overview of microRNA expression patterns

Abstract: Pre-eclampsia (PE) is strongly associated with heart failure (HF) later in life. During PE pregnancy, the left ventricle undergoes concentric remodeling which often persists after delivery. This aberrant remodeling can induce a molecular signature that can be evaluated in terms of microRNAs (miRNAs) and which may help to explain the associated increased risk of HF. For this review, we performed a literature search of PubMed (National Center for Biotechnology Information), identifying studies on miRNA expressio… Show more

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Cited by 24 publications
(15 citation statements)
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“…11 In a self-controlled case series study of patients with HF, influenza vaccination was associated with a significantly lower risk of cardiovascular, respiratory, and all-cause hospitalization. 43 In a meta-analysis of 16 studies of patients with CVD, influenza vaccination was associated with a lower risk of all-cause, cardiovascular mortality, and major adverse cardiovascular events compared with control patients. 15 In the Cardiovascular Health Study, pneumococcal vaccination was associated with significant reductions in incident HF, all-cause mortality, and cardiovascular mortality.…”
Section: Stage C Hfmentioning
confidence: 99%
“…11 In a self-controlled case series study of patients with HF, influenza vaccination was associated with a significantly lower risk of cardiovascular, respiratory, and all-cause hospitalization. 43 In a meta-analysis of 16 studies of patients with CVD, influenza vaccination was associated with a lower risk of all-cause, cardiovascular mortality, and major adverse cardiovascular events compared with control patients. 15 In the Cardiovascular Health Study, pneumococcal vaccination was associated with significant reductions in incident HF, all-cause mortality, and cardiovascular mortality.…”
Section: Stage C Hfmentioning
confidence: 99%
“…Furthermore, Mohseni et al . recently reviewed the overlap between microRNA (miRNA) expression in concentric (aberrant) cardiac remodeling in response to the volume load of pregnancy and in PE.…”
Section: Cardiovascular Predisposition To Pre‐eclampsiamentioning
confidence: 99%
“…preeclampsia (8,9). Additionally, the potential involvement of miRNAs in peripartum cardiomyopathy is the subject of only a limited number of published studies (10,11).…”
Section: Downregulated Expression Of Micrornas Associated With Cardiamentioning
confidence: 99%
“…Studies of the role of miRNAs in cardiovascular alterations associated with pregnancy is limited primarily to preeclampsia ( 8 , 9 ). Additionally, the potential involvement of miRNAs in peripartum cardiomyopathy is the subject of only a limited number of published studies ( 10 , 11 ).…”
Section: Introductionmentioning
confidence: 99%