Cardiac, respiratory, and motor activity in norm and after activation of catecholaminergic systems in newborn rat pups

Кузнецов, С. В.; Dmitrieva, L. E.; Sizonov, V. A.

doi:10.1134/s002209301204007x

Cited by 9 publications

(4 citation statements)

References 23 publications

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“…Results included cardiovascular, respiratory, and somatomotor activity parameters in dynamics. The experiments were conducted in intact and test animals that were exposed to physiological and pharmacological activation of dopaminergic and noradrenergic systems [26][27][28][29].…”

Section: Monoaminergic Regulation Of Rhythmic Activity During Perinatmentioning

confidence: 99%

Ontogenetic Development of Neural and Muscular Rhythmic Activity and Its Regulation in Mammals during Perinatal Period

Кузнецов¹,

Vdovichenko²,

Dmitrieva³

et al. 2018

Evolutionary Physiology and Biochemistry - Advances and Perspectives

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This review covers our recent advantages in studying the ontogenetic aspects of physiological mechanisms underlying regulation of rhythmic behavior. We have revealed that excitation patterns that emerged at early stages of phylogenetic development of life forms contribute greatly to the rhythmic activity of living vertebrates and invertebrates. These patterns govern spontaneous excitation, which is easily observed during the early stage of ontogenesis. The intensity and patterns of rhythmic activity are determined by nature and kinetics of certain metabolic reactions. During perinatal and sometimes postnatal periods (as in prematurely born animals), endogenic rhythmicity of developing physiological structures is strongly pronounced due to relatively stable living conditions. This rhythmic behavior is coordinated within an entire organism. Its integration in multiple systems is driven by amplitude and frequency modulation yielding rhythms of various frequency ranges. Indeed, it is the complex and conjoint functioning of physiological systems that maintains homeostasis in developing organisms. We present the results of our authentic research concerning the evolution and ontogeny of regulatory mechanisms of motor, cardiovascular, and respiratory systems. The aspects of intact and disrupted development are considered, involving the changes in dopaminergic, norepinephrinergic, and cholinergic system activation.

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Section: Monoaminergic Regulation Of Rhythmic Activity During Perinatmentioning

confidence: 99%

Ontogenetic Development of Neural and Muscular Rhythmic Activity and Its Regulation in Mammals during Perinatal Period

Кузнецов¹,

Vdovichenko²,

Dmitrieva³

et al. 2018

Evolutionary Physiology and Biochemistry - Advances and Perspectives

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show abstract

“…KUZNETSOV et al and the bursts of the motor activity (MA) are separated by the rest periods producing the deca-second, near-minute, and many-minute cycles "activity-rest" [12]. MA of the gastrocnemius and neck muscles is of the generalized character and has comparable values of the EMG power.…”

Section: 7mentioning

confidence: 99%

“…The most part of the studies have the descriptive character and contain only the qualitative parameters. It has been established that some correlations exist between the character of activity in the somato-motor system and in other functional systems: CNS [1][2][3], digestive tract [4], circulatory and respiratory systems [5][6][7][8][9][10][11][12]. There are studies considering interactions between activity of the respiratory system and variability of the cardiac rhythm [13][14].…”

Section: Introductionmentioning

confidence: 99%

“…The interaction between activity of the somato-motor and circulatory systems is increased in the rat pups as early as for the first hours after birth. The cardinal change of functioning of the respiratory system occurs after the animal birth, and, correspondingly, the character of its interaction with other excitatory systems of organism is changed [12].…”

Section: Introductionmentioning

confidence: 99%

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Change of character of intersystemic interactions in newborn rat pups under conditions of a decrease of central influences (urethane anesthesia)

Кузнецов

Sizonov

Dmitrieva

2014

J Evol Biochem Phys

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On newborn rat pups, for the first day after birth, there was studied the character of mutual influences between the slow-wave rhythmical components of the cardiac, respiratory, and motor activities reflecting interactions between the main functional systems of the developing organism.The study was carried out in norm and after pharmacological depression of the spontaneous periodical motor activity (SPMA) performed by narcotization of rat pups with urethane at low (0.5 g/kg, i/p) and maximal (1 g/kg, i/p) doses. Based on the complex of our obtained data, it is possible to conclude that after birth in rat pups the inter-systemic interactions are realized mainly by the slow-wave oscillations of the near-and manyminute diapason. The correlational interactions mediated by rhythms of the decasecond diapason do not play essential role in integrative processes. Injection to the animals of urethane producing selective suppression of reaction of consciousness, but not affecting activating influences of reticular formation on cerebral cortex does not cause marked changes of autonomous parameters, but modulates structure and expression of spontaneous periodical motor activity. There occurs an essential decrease of mutual influences between motor and cardiovascular systems. In the case of preservation of motor activity bursts, a tendency for enhancement of correlational relations between the modulating rhythms of motor and somatomotor systems is observed. The cardiorespiratory interactions, more pronounced in intact rat pups in the near-and manyminute modulation diapason, under conditions of urethane, somewhat decrease, whereas the rhythmical components of the decasecond diapason-are weakly enhanced.

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Changes in Activities of Somatovisceral Systems in Newborn Rats under Conditions of Nicotinic Cholinoreceptor Blockage and Activation of Cholinoreactive Structures

Sizonov

Dmitrieva

2019

Bull Exp Biol Med

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Cardiac, respiratory, and motor activity in norm and after activation of catecholaminergic systems in newborn rat pups

Cited by 9 publications

References 23 publications

Ontogenetic Development of Neural and Muscular Rhythmic Activity and Its Regulation in Mammals during Perinatal Period

Ontogenetic Development of Neural and Muscular Rhythmic Activity and Its Regulation in Mammals during Perinatal Period

Change of character of intersystemic interactions in newborn rat pups under conditions of a decrease of central influences (urethane anesthesia)

Changes in Activities of Somatovisceral Systems in Newborn Rats under Conditions of Nicotinic Cholinoreceptor Blockage and Activation of Cholinoreactive Structures

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