Cardiac resynchronization therapy in chronic heart failure: Effect on right ventricular function

Perspective and future direction of intraventricular mechanical dyssynchrony assessment

“…If a patient with HF and severely depressed LVEF does not respond to pharmacological treatment, CRT should be considered ( Figure 1-1st); before the appearance of a branch block or an increase in the duration of the QRS complex. 9,10 Why? because there may be ventricular mechanical dyssynchrony without branch block with normal QRS 9 ( Figure 2); and although electrical and mechanical dyssynchrony often coincide, electrical and mechanical dyssynchrony are commonly not present at the same time in a given patient.…”

New insights in the assessment of left ventricular dyssynchrony: Laying the foundations for phase analysis by cardiac SPECT

“…13 In view of the emerging evidence that LV dyssynchrony can be accurately assessed by phase analysis from cardiac SPECT MPI and may predict CRT response, it brings new hope for the challenges that physicians face in the management of patients with chronic heart failure. 14,15…”