2008
DOI: 10.1093/europace/eun064
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Cardiac resynchronization therapy in patients with heart failure and atrial fibrillation: importance of new-onset atrial fibrillation and total atrial conduction time

Abstract: Failure to CRT is associated with new-onset AF. Total atrial activation time may be a parameter to predict response in AF patients.

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Cited by 33 publications
(28 citation statements)
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“…In both analyses, the overall effect was statistically significant (p=0.008 and p=0.005, respectively), with no evidence of heterogeneity between studies (I 2 =0%) ( Figure 5). In four studies analyzed, the likelihood of non-response to CRT was 69% lower in patients treated by ablation (OR: 0.31; 95% CI: 0.10---0.97; p=0.04; I 2 =72% Molhoek et al 9 Gasparini et al 40 Delnoy et al 18 Tolosana et al 15 Kim et al 13 Buck et al 12 Wo et al 11 Wilton et al 17 Tolosana …”
Section: The Role Of Atrioventricular Nodal Ablationmentioning
confidence: 98%
See 1 more Smart Citation
“…In both analyses, the overall effect was statistically significant (p=0.008 and p=0.005, respectively), with no evidence of heterogeneity between studies (I 2 =0%) ( Figure 5). In four studies analyzed, the likelihood of non-response to CRT was 69% lower in patients treated by ablation (OR: 0.31; 95% CI: 0.10---0.97; p=0.04; I 2 =72% Molhoek et al 9 Gasparini et al 40 Delnoy et al 18 Tolosana et al 15 Kim et al 13 Buck et al 12 Wo et al 11 Wilton et al 17 Tolosana …”
Section: The Role Of Atrioventricular Nodal Ablationmentioning
confidence: 98%
“…O grupo com doentes em FA apresenta maior risco de mortalidade total, comparativamente ao grupo de doentes em RS (OR=1,69; IC 1,37, p=0,002). Não foram verificadas diferenças estatisticamente significativas quanto à mortalidade cardiovascular (OR=1,36, IC 0,01, p=0,12). A não resposta à TRC foi maior no grupo em FA (OR=1,41; IC 1,15---1,73; p=0,001).…”
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“…9 Approximately 15 to 25% of the patients treated with CRT develop new onset AF during follow-up. 12,13 AF during followup may reduce the effectiveness of cardiac resynchronisation therapy due to high ventricular heart rates, especially during (moderate) exercise. Consequently, the development of newonset AF should be closely monitored.…”
Section: N T E R U N I V E R S I T Y C a R D I O L O G Y I N S T I mentioning
confidence: 99%
“…Due to the high prevalence of AF in HF patients who meet indications for an implantable cardioverter defibrillator (ICD) [18,19], this combined therapy could treat HF, prevent sudden cardiac death, prevent AF and restore sinus rhythm when necessary. As AF may compromise the efficacy of CRT in terms of reverse remodeling [20,21] a break in the AF/HF cycle could improve prognosis both by optimizing HF treatment and restoring sinus rhythm. The TRADE-HF study has been designed to assess the benefits of an automatic, device-based management of atrial arrhythmias in patients suffering from symptomatic HF, indicated for CRT treatment with defibrillation backup and implanted with a dual (atrial and ventricular) defibrillator.…”
Section: Introductionmentioning
confidence: 99%