A robust generalized labeled multi-Bernoulli (GLMB) filter is presented to perform multitarget tracking (MTT) with unknown non-stationary heavy-tailed measurement noise (HTMN). The HTMN is modeled as a multivariate Student's t-distribution with unknown and time-varying mean. The proposed filter relaxes the restrictive assumption that the mean of HTMN is zero, and can effectively deal with MTT under the condition that the mean of HTMN is unknown and time-varying. The variational Bayesian (VB) approximation is applied in the GLMB filtering framework with the augmented state. The marginal likelihood function is obtained via minimizing the Kullback-Leibler divergence by the variational lower bound. The simulation results demonstrate that the proposed filter can effectively track multiple targets in both linear and nonlinear scenarios when the mean of HTMN is unknown and time-varying.INDEX TERMS Generalized labeled multi-Bernoulli filter, multitarget tracking (MTT), variational Bayesian (VB), non-stationary, heavy-tailed measurement noise (HTMN), unknown and time-varying mean.