Cardio-Ankle Vascular Index as an Arterial Stiffness Marker Improves the Prediction of Cardiovascular Events in Patients without Cardiovascular Diseases

Okamoto, Yuko; Miyoshi, Toru; Ichikawa, Keishi; Takaya, Yoichi; Nakamura, Kazufumi; Ito, Hiroshi

doi:10.3390/jcdd9110368

Cited by 5 publications

(3 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…26 CAVI may have higher discrimination in all-cause mortality and major adverse cardiovascular endpoints. 27 CAVI is a more stable indicator, CAVI has the advantages of non-invasive, immune to blood pressure, and inexpensive. Generally, arteriosclerosis detectors can measure CAVI and ankle brachial index(ABI), and can be considered for large-scale vascular screening in the future.…”

Section: Evaluation Of Arteriosclerosismentioning

confidence: 99%

Vascular Health Promotion Project and Vascular Medicine in China-CCVM2004-2023

Wen,

Jiang,

Yuan

et al. 2023

VHRM

View full text Add to dashboard Cite

Cardiovascular disease(CVD) has become a major disease burden affecting people's health in China. Blood vessels are very important for human health and are the "sentinel" for the development of many cardiovascular and cerebrovascular diseases. The key to effectively preventing fatal, disabling heart, brain and peripheral vascular events lies in controlling traditional and nontraditional risk factors for vascular health from the source, and early assessment and intervention of early vascular lesions. Since 2004, China government promoted the early detection technology of vascular lesions and vascular medicine, and proposed the Beijing Vascular Health Stratification (BVHS) to provide suggestions for the examination, evaluation and management of risk factors, and to provide new ideas for lifelong maintenance of vascular health. This review mainly introduces the establishment and development of the clinical discipline of "vascular medicine" in the past 20 years in China, introduces the indicators for detecting vascular function and structure and the predictive value of vascular events, and carries out intelligent and digital management of vascular health throughout the life cycle of individualized prevention, treatment and rehabilitation for people with different parts or degrees of lesions, effectively reducing the occurrence and development of cardiovascular and cerebrovascular diseases, and the prospect of new technology in maintaining vascular health.

show abstract

Section: Evaluation Of Arteriosclerosismentioning

confidence: 99%

Vascular Health Promotion Project and Vascular Medicine in China-CCVM2004-2023

Wen,

Jiang,

Yuan

et al. 2023

VHRM

View full text Add to dashboard Cite

show abstract

“…The cardio–ankle vascular index (CAVI) is acknowledged as a blood pressure-independent marker of arterial stiffness across the entire arterial system, extending from the aortic root to the ankle [ 13 ]. Previous studies have reported that an abnormal CAVI value (>9.0) is associated with a significant incidence of cardiovascular events, including cardiovascular death, myocardial infarction, stroke, hospitalization for HF, and coronary revascularization [ 14 ]. Therefore, arterial stiffness and VO 2 are prognostic factors for cardiovascular disease, although the relationship between arterial stiffness and VO 2 in patients with AMI remains unclear.…”

Section: Introductionmentioning

confidence: 99%

Determination of Peak Oxygen Uptake in Patients with Acute Myocardial Infarction: The Role of Arterial Stiffness in Cardio–Vascular–Skeletal Muscle Coupling

Ogawa,

Kanzaki,

Ikeda

et al. 2023

JCM

View full text Add to dashboard Cite

The relationship between arterial stiffness and oxygen uptake (VO2) in patients with acute myocardial infarction (AMI) remains unclear. We aimed to investigate this relationship and factors contributing to VO2 in patients with AMI. The role of arterial stiffness in cardio–skeletal muscle coupling during exercise was then elucidated. Upon discharge, we measured exercise capacity using cardiopulmonary exercise testing (CPX), assessed arterial stiffness with the cardio–ankle vascular index (CAVI), and determined body composition to assess the skeletal muscle mass of 101 patients with AMI. Patients were categorized based on their CAVI scores into three groups: (i) normal (CAVI: ≤7.9), (ii) borderline (CAVI: 8.0–8.9), and (iii) abnormal (CAVI: ≥9.0). Subsequently, VO2 was compared among these groups. The relationship between the CAVI and VO2 Peak during CPX and factors contributing to VO2 Peak were investigated. The abnormal CAVI group had a significantly lower VO2 Peak than the normal and borderline groups. The CAVI was associated with VO2 Peak. Furthermore, the CAVI was found to be a factor contributing to VO2 Peak. These findings suggest that arterial stiffness in tissue blood distribution and blood supply causes systemic exercise limits in patients with AMI. This suggests that arterial stiffness plays a significant role in cardio–vascular–skeletal muscle coupling.

show abstract

“…A retrospective, single-center cohort study including outpatients with cardiovascular disease risk factors but without known cardiovascular disease evaluated the prognostic impact of cardio-ankle vascular index (CAVI) [ 8 ]. Importantly, results showed that CAVI improved the prediction of cardiovascular events (the addition of CAVI to a conventional risk score for coronary heart disease in Japan significantly improved the C statics from 0.642 to 0.713; p = 0.04) [ 8 ].…”

mentioning

confidence: 99%