Cardio-metabolic risk factors in Argentine children. A comparative study

Sobrero, Angela Figueroa; Evangelista, Patrícia Gonçalves; Kovalskys, Irina; Digón, Patricia; López, Stella; Scaiola, Edit; Pérez, Norma; Dieuzeide, Guillermo; Walz, Florencia; Mazza, Carmen

doi:10.1016/j.dsx.2015.10.003

Cited by 9 publications

(4 citation statements)

References 36 publications

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“…Recently, IR is increasingly observed in children with obesity [ 18 , 19 ]. While this can be a consequence of the rising prevalence of obesity at younger age, recent studies also hypothesized other risk factors, such as preterm birth, low birth weight, absence of breastfeeding, and family history of diabetes and obesity [ 4 , 18 – 20 ].…”

Section: Introductionmentioning

confidence: 99%

Predictors of Insulin Resistance in Children versus Adolescents with Obesity

et al. 2017

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Introduction Obesity is a risk factor to develop metabolic syndrome (MetS) and type 2 diabetes mellitus (T2DM). Insulin resistance (IR) plays a major part in both. With increasing incidence of childhood obesity, this retrospective study aimed to identify predictors of IR in children/adolescents with obesity to optimize screening for IR. Method Patients aged ≥ 2–≤ 18 years with obesity (BMI-SDS > 2.3) were included. IR was defined as HOMA-IR ≥ 3.4, and MetS if ≥3 of the following criteria were present: waist circumference and blood pressure ≥ 95th age percentile, triglycerides ≥ 1.7 mmol/l, HDL < 1.03 mmol/l, and fasting plasma glucose ≥ 5.6 mmol/l. Results In total, 777 patients were included. Of the 306 children, 51, 38, and 0 were diagnosed with IR, MetS, and T2DM, respectively. Of the 471 adolescents, 223, 95, and 0 were diagnosed with IR, MetS, and T2DM, respectively. In the multivariable regression model, BMI-SDS, preterm birth, and Tanner stage were associated with IR in children (6.3 (95% CI 1.3–31.1), 5.4 (95% CI 1.4–20.5), 2.2 (95% CI 1.0–4.8)), and BMI-SDS and waist circumference in adolescents (4.0 (95% CI 1.7–9.2), 3.7 (95% CI 1.5–9.4)). Conclusion Different IR predictors were observed in children/adolescents with obesity. These predictors can be used to optimize screening for IR in pediatric populations.

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Section: Introductionmentioning

confidence: 99%

Predictors of Insulin Resistance in Children versus Adolescents with Obesity

et al. 2017

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“…(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24). MetS prevalence ranges from 10% (23) to 57.4% (17) in obese children and adolescents, and it increases with BMI (14,16,18,23,25,26). It is difficult to compare the prevalence of MetS in children across studies because of the numerous diverse criteria employed in its many classifications.…”

Section: Discussionmentioning

confidence: 99%

Evaluation Of Sims Score As A Marker Of Metabolic Syndrome In Children With Simple Obesity

Abo Elgheet,

Taha,

Metwalley

et al. 2024

Journal of Current Medical Research and Practice

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“…BMI is also controversial because it does not distinguish between fat and fat‐free mass, and does not provide information on the distribution of body fat. This aspect is essential because the location of excess fat tissue accumulation is more significant than the amount of total fat, as a co‐morbidity triggering factor in children and adolescents (Ali et al, 2014; Figueroa Sobrero et al, 2016; Viitasalo et al, 2019). Consistent with adult observations, waist circumference (WC) in children is a predictor independent from insulin resistance, lipid levels, and blood pressure (Zimmet et al, 2007).…”

Section: Introductionmentioning

confidence: 99%

Waist circumference percentiles for Hispanic‐American children and comparison with other international references

Serrano

Román

Carmenate

et al. 2020

American J Hum Biol

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Introduction Waist circumference (WC) constitutes an indirect measurement of central obesity in children and adolescents. Objective To provide percentiles of WC for Hispanic‐American children and adolescents, and compare them with other international references. Materials and methods The sample comprised 13 289 healthy children between 6 and 18 years coming from public schools of middle and low socioeconomic levels in different parts of Argentina, Cuba, Spain, Mexico, and Venezuela. The LMS method to calculate WC percentiles was applied. Sex and age differences were assessed using Student's t test and ANOVA (SPSS v.21.0). Comparisons were established with references from the United States, Colombia, India, China, Australia, Kuwait, Germany, Tunisia, Greece, and Portugal. Results WC increases with age in both sexes. Boys show higher WC in P3, P50, and P97. Comparison of 50th and 90th percentiles among populations from diverse sociocultural and geographical contexts shows high variability, not all justified by the measurement method. Discussion and conclusions Specific WC percentiles for sex and age, and P90 cut‐off points are provided; these values are potentially useful to assess central obesity in Hispanic‐American adolescent children.

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Cardio-metabolic risk factors in Argentine children. A comparative study

Cited by 9 publications

References 36 publications

Predictors of Insulin Resistance in Children versus Adolescents with Obesity

Predictors of Insulin Resistance in Children versus Adolescents with Obesity

Evaluation Of Sims Score As A Marker Of Metabolic Syndrome In Children With Simple Obesity

Waist circumference percentiles for Hispanic‐American children and comparison with other international references

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