Cardiogenic shock

Effect of Tilarginine Acetate in Patients With Acute Myocardial Infarction and Cardiogenic Shock

“…[1][2][3][4][5][6][7][8] Early revascularization improves survival; however, early mortality rates remain high, particularly among patients with continued shock after revascularization. 9 The understanding of the pathophysiology of cardiogenic shock complicating MI has recently evolved toward an appreciation of the role of systemic inflammation, including cytokine release and expression of inducible nitric oxide synthase (NOS).…”

Effect of Atropine on Bradycardia and Hypotension in Acute Myocardial Infarction

“…Atropine has been mentioned as beneficial in treating bradycardia in acute myocardial infarction (Agress and Binder, 1957), but measurements of the circulatory consequences are not recorded. We have found atropine to be effective in raising heart rate and arterial blood pressure in circumstances where these have been consistently low or have fallen acutely.…”

Mechanism of Cardiogenic Shock

“…11 Recently, Agress and Binder 6 reappraised the problem of cardiogenic shock and described two types of hemodynamic responses following experimental coronary embolism: (a) severe fall in cardiac output (to 50 per cent of control value), associated with a well-maintained blood pressure owing to a rise in peripheral resistance, and (b) a similar fall in cardiac output, but a low mean arterial blood pressure (G' O per cent of control). In this latter group, the total peripheral resistance showed no tendency to increase and so compensate for the falling cardiac output.…”