Cardiomiopatia de Takotsubo Recorrente: Um Enigma ainda não Resolvido

COVID-19 and Takotsubo Cardiomyopathy: An integrative review

“…The word "Takotsubo" refers to a Japanese fishing vessel for catching octopus, which has a circular bottom and narrow neck and resembles the shape of a heart in CT. Also known as broken heart syndrome, it is a rare dysfunction that affects the left ventricular (LV) systolic function, resulting from an abrupt and intense discharge of catecholamines (triggered by physical or emotional stressors), of a transient and reversible nature [3,4]. Its clinical presentation is very similar to acute coronary syndrome, corresponding to approximately 2% of patients who present with acute chest pain and dyspnea, in addition to changes in the electrocardiogram and increase in biomarkers of cardiac injury, but on CT there is no significant coronary stenosis (no coronary artery disease) at the injured site.…”

“…Conditions such as overstimulation of the sympathetic system, abnormality of microvascular and myocardial tissue metabolism, and coronary artery vasospasm have been linked to CT. In addition, lower body mass index (BMI), previous mid-ventricular gradient, female gender, and temporal proximity to a first event were associated with the recurrence of this syndrome [3,4].…”