Cardiomyocyte ultrastructure in the perifocal zone of an experimental myocardial infarct in rats treated with the hexapeptide dalargin

On some pathogenetic and adaptation mechanisms of acute coronary disease

“…However, subsequent course and outcome of the disease depend on what, specifically, developed in the myocardium -a necrotic focus or reversible dystrophy. Importantly, that in obvious myocardial infarction the area of macroscopically intact myocardium bordering the necrotic area is also subjected to morphological and ultrastructural changes to this or that measure [4]. Therefore, it is important to study the pathogenetic, defense, and adaptive mechanisms, developing in the course of acute disorders of coronary circulation in ischemic, but still viable myocardium.…”

Opioid peptides modulate secretion of the basic determinants of bile secretion

“…It was demonstrated that opioid peptides (OP) modify stress reaction [5], acting as a stress-limiting system factor. They produce a protective effect in myocardial ischemia [7]. These peptides modulate the release of neurotransmitters and conductivity of neuronal membrane [12], They also produce a wide range of biological effects on the digestive system.…”