Cardiomyopathies (hypertrophy and failure): What can offer cardiac magnetic resonance imaging?

Silvera, S.; Strach, Katharina; Bogaert, Jan; Sommer, Torsten; Vignaux, O.

doi:10.1016/j.lpm.2010.12.016

Cited by 6 publications

(5 citation statements)

References 71 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Technically, we found difficulty to null the myocardial signal due to rapid washout from the blood pool and high myocardial uptake in the affected areas with amyloid deposition. To visualize myocardial and blood pool kinetics we used inversion time scout at 5 min after contrast administration as recommended in the previous study (22) .…”

Section: Discussionmentioning

confidence: 99%

Could Cardiac MR Imaging with Late Gadolinium Enhancement Affect The Risk Stratification and Outcome Prediction In Non-Ischemic Cardiomyopathies?

Sameeh¹,

Sayed²,

Othman³

et al. 2022

The Egyptian Journal of Hospital Medicine

View full text Add to dashboard Cite

Background: Cardiac MR (CMR) evaluating non-ischemic cardiomyopathies (NICMs) is superior 3D imaging with noninvasiveness, more accuracy and reproducibility of measurements. It provides comprehensive structural, functional information, tissue characterization, and assesses fibrosis by LGE.Objective: The study aimed to investigate these imaging data and their prognostic value in NICM. Patients and methods: 46 NICM patients were assessed by echocardiography/cardiac magnetic resonance (CMR). They were divided into 3 groups: dilated, hypertrophic and miscellaneous types. Late gadolinium enhancement (LGE) presence and myocardial extent/percentage were assessed with clinical follow up for a median of 1-year for any Major adverse cardiac events (MACE). For each group, univariate analysis of clinical/imaging risk factors in the associations with LGE/MACE was performed. Results: Twenty-six dilated cardiomyopathy patients, 62% had LGE and 31% had MACE. Using LGE as a predictor for MACE was statistically significant (p = 0.007). Using univariate analysis, the presence of LGE (p=0.00) and the extent of LGE (p < 0.0001) demonstrated the strongest unadjusted association with MACE. ROC curves revealed a cutoff value of LGE > 4.5% as MACE predictor. Twelve hypertrophic cardiomyopathy patients (67%) had LGE and (50%) had MACE. Using LGE as a predictor for MACE was statistically significant (p=0.014). Using univariate analysis, the presence of LGE (p=0.01) and the extent of LGE (p=0.01) demonstrated the strongest unadjusted association with MACE. ROC curves revealed a cutoff value of LGE > 4.5% as MACE predictor. Conclusion: CMR with LGE is crucial in NICM evaluation with prognostic value; changing the way that myocardial disorders will be understood and managed in the near future.

show abstract

Section: Discussionmentioning

confidence: 99%

Could Cardiac MR Imaging with Late Gadolinium Enhancement Affect The Risk Stratification and Outcome Prediction In Non-Ischemic Cardiomyopathies?

Sameeh¹,

Sayed²,

Othman³

et al. 2022

The Egyptian Journal of Hospital Medicine

View full text Add to dashboard Cite

show abstract

“…This systematic review will allow determination as to whether CMR is an adequate screening test in the diagnosis of significant obstructive CAD. It will also determine if CMR could replace FFR for diagnosing coronary arterial lesions that are haemodynamically significant, and allow consideration of the potential benefit of CMR in diagnosing ischaemic [27] and non-ischaemic myocardial pathologies [28-30] without exposing patients to ionising radiation. This systematic review may also identify the type of CMR magnetic field strength that could provide the greatest sensitivity and specificity.…”

Section: Discussionmentioning

confidence: 99%

Magnetic resonance myocardial perfusion imaging in the diagnosis of functionally significant obstructive coronary artery disease: a systematic review protocol

et al. 2014

View full text Add to dashboard Cite

BackgroundCardiac magnetic resonance (CMR) myocardial perfusion imaging has been suggested as a non-invasive alternative to pressure wire guided fractional flow reserve (FFR) in detecting haemodynamically significant obstructive coronary artery disease (CAD). The objective of this systematic review is to determine the diagnostic accuracy of CMR and to compare it to FFR.Methods/designA systematic review of diagnostic test accuracy of CMR and FFR will be conducted. Relevant English-language articles published before November 2013 in Medline, PubMed, EMBASE, Google scholar, Scopus and Cochrane databases will be identified. Relevant referenced articles from those selected will also be analysed. Articles describing diagnostic studies that compared CMR to FFR in patients with known or suspected coronary artery disease will be included. Two investigators will independently screen, assess quality and extract data from the selected articles. The Quality Assessment of Diagnostic Accuracy Studies 2 (QUADAS-2) tool will be used to assess methodological quality. STATA 13 (the xtmelogit command) software will be used to calculate bivariate random effects models and estimate pooled sensitivity and specificity with 95% confidence intervals. Forests plots and summary receiver operating characteristics curves will also be generated. Sub-group pooled analyses using image quality of CMR (in terms of magnetic flux density - Tesla) and basis of analyses (coronary arterial territory vs. patients basis) at different FFR cutoffs (≤0.75 and ≤0.8) will also be performed.DiscussionThis systematic review will help to determine if CMR is an adequate alternative to FFR in the diagnosis of significant and obstructive CAD. We will also be able to assess diagnostic accuracy of specific types of CMR scan at different FFR cutoffs.Systematic review registrationThis systematic review had been registered at PROSPERO and the registration number is CRD42013006180.

show abstract

“…Cardiac involvement is clinically silent in most patients, but some ECG signs may guide the diagnosis, such as complete heart block and ventricular arrhythmias, right bundle branch block, and SDC [ 49 ]. Since cardiac sarcoidosis (CS) is responsible for morbidity and mortality, early diagnosis is important to prevent severe consequences; it also guides corticosteroid therapy to prevent cardiac arrhythmias and to improve LV function [ 49 , 50 ].…”

Section: Infiltrative Heart Diseasesmentioning

confidence: 99%

“…Cardiac involvement occurs in the typical three stages of the disease: acute myocardial inflammation, post-inflammatory pattern, and replacement scarring [ 50 ]. CMR represents a crucial non-invasive and advanced imaging test with a diagnostic and prognostic value, able to reach an early diagnosis of CS [ 49 , 51 ], because of the high spatial resolution and the ability of evaluating left and right ventricular function, combined with tissue characterization [ 51 ].…”

Section: Infiltrative Heart Diseasesmentioning

confidence: 99%

Cardiac magnetic resonance of hypertrophic heart phenotype: A review

Faletti

Gaetani

Bozzo

et al. 2023

Heliyon

View full text Add to dashboard Cite

Cardiomyopathies (hypertrophy and failure): What can offer cardiac magnetic resonance imaging?

Cited by 6 publications

References 71 publications

Could Cardiac MR Imaging with Late Gadolinium Enhancement Affect The Risk Stratification and Outcome Prediction In Non-Ischemic Cardiomyopathies?

Could Cardiac MR Imaging with Late Gadolinium Enhancement Affect The Risk Stratification and Outcome Prediction In Non-Ischemic Cardiomyopathies?

Magnetic resonance myocardial perfusion imaging in the diagnosis of functionally significant obstructive coronary artery disease: a systematic review protocol

Cardiac magnetic resonance of hypertrophic heart phenotype: A review

Contact Info

Product

Resources

About