Cardiopulmonary bypass: development of John Gibbon's heart-lung machine

Passaroni, Andréia Cristina; Silva, Marcos Augusto de Moraes; Yoshida, Winston Bonetti

doi:10.5935/1678-9741.20150021

Cited by 44 publications

(50 citation statements)

References 35 publications

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“…Previous studies also found the same results (21)(22)(23)(24). Some researchers also reported increased sodium levels after liver transplant is associated with postoperative complications (13)(14)(15)(16)(25)(26)(27)(28)(29).…”

Section: Discussionsupporting

confidence: 72%

Association of Perioperative Serum Sodium Level Fluctuation and Postoperative Complications in Coronary Artery Bypass Graft Surgery

Azarfarin

Shekoohi

Totonchi

et al. 2017

Multidiscip CardioAnnal

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Background: Electrolyte abnormalities are common in coronary artery bypass graft surgery (CABG) using cardiopulmonary bypass (CPB). Changes in serum sodium (Na) concentration more than 15 meq/L in perioperative period (Delta Na > 15) is considered as significant fluctuation. The aim of this study was evaluating the relationship between the significant fluctuation of serum Na level and the complications after coronary artery bypass graft surgery. Methods: In this prospective observational study 59 patients who were candidates for CABG with CPB were enrolled into the study. We recorded patients' demographic data, arterial blood gas analysis (ABG), serum electrolytes including Na levels from anesthesia induction, during and after CPB up to 24 hours after admission in ICU. Postoperative complications until discharge from ICU were compared between patients with significant Na fluctuation and those without it.Results: Thirty-nine patients had serum sodium fluctuation equal and more than 15 mEq/L (Delta Na ≥ 15 group). This group was compared with those who had minor Na variation (Delta Na < 15; n = 20). The Na > 15 mEq/L fluctuation group had higher serum Na and lactate levels, lower base excess in ABG. Patients with at least one postoperative complication, were older and had lower ejection fraction and more sodium fluctuations. Logistic regression analysis showed that serum sodium fluctuation more than 15mEq/l was independently associated with post CABG complications. Conclusions: Perioperative serum sodium fluctuation more than 15mEq/L was independently associated with postoperative complications in patients undergoing CABG.

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Section: Discussionsupporting

confidence: 72%

Association of Perioperative Serum Sodium Level Fluctuation and Postoperative Complications in Coronary Artery Bypass Graft Surgery

Azarfarin

Shekoohi

Totonchi

et al. 2017

Multidiscip CardioAnnal

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“…Despite several effective approaches including prone positioning and low tidal volume ventilation, acute respiratory distress syndrome [17] still has a mortality of more than 40% and affects about 10% of ICU patients. Extracorporeal lung support was introduced more than 80 years ago with Gibbon's heart-lung machine [18]. The first case reports on the clinical use of ECMO in ARDS and preterm infants were published in the 1970s.…”

Section: Extracorporeal Lung Support: Oxygenationmentioning

confidence: 99%

Options in extracorporeal support of multiple organ failure

Huber

Garibay²

2020

Med Klin Intensivmed Notfmed

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“…The development of the heart-lung machine in the 1930's was an important landmark for cardiac surgery as it enabled tissue perfusion while the heart was stopped and provided a bloodless field for surgery. 19 The basic cardiopulmonary bypass (CPB) circuit consists of venous cannula, tubing, reservoir, pump, heat exchanger, oxygenator, tubing, arterial cannula, and cardioplegia cannula. The system allows venous blood to be drained from the heart, oxygenated, and returned to circulation, thereby taking over the natural functions of the heart and lungs.…”

Section: Cardiopulmonary Bypassmentioning

confidence: 99%

“…The system allows venous blood to be drained from the heart, oxygenated, and returned to circulation, thereby taking over the natural functions of the heart and lungs. 19 However, there are complications associated with CPB which can be broadly divided into mechanical and systemic types.…”

Section: Cardiopulmonary Bypassmentioning

confidence: 99%

Complications of Coronary Artery Bypass Grafting

Hussain

Harky

2019

Int J Med Rev

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Introduction Coronary artery bypass grafting (CABG) is one of the most commonly performed operations with approximately 200 000 procedures performed annually in the United States of America and an incidence of 62 per 200 000 inhabitants in Western Europe. 1 It has evolved over the past century from a high-risk procedure to a relatively safe one with a current mortality rate of 1%-2% in elective patients. 2 Nonetheless, it is still a highly complex surgery and has been associated with a number of complications. The complications from this major surgery can be classified in various ways; some are catastrophic, such as death and stroke, while others can be self-limiting without any long-term residual effects, such as atelectasis, lower respiratory infection, or transient acute kidney injury. 2,3 CABG can be considered as a large operation incorporating many smaller operations. There may be variations in these smaller operations that can have both advantages and disadvantages. However, the end goal is to bypass a blocked or narrow coronary artery by anastomosis of a vessel conduit. 3 This may be done with or without cardio-pulmonary bypass, with arterial or venous grafts, and with open or endoscopic harvesting of conduits. The overall risk of this operation is determined by the Euroscore, which is a statistical determination of risk using logistic regression. 4,5 It is determined by patient-related factors (age, gender, renal impairment, peripheral vascular disease, mobility, previous cardiac surgery, chronic lung disease, active endocarditis, critical pre-operative state, insulin dependent diabetes), cardiac-related factors (NYHA dyspnea classification, CCS angina classification, left ventricular function, recent myocardial infarction, and pulmonary hypertension) and operation factors (urgency, weight of intervention, and involvement of thoracic aorta). 5 For the purposes of valid patient consent, it is considered mandatory to discuss the risk of death, peri-operative myocardial infarction, stroke, and sternal wound infection. 6 The general complications of CABG surgery are briefly discussed below followed by a discussion of the specific complications associated with cardiopulmonary bypass and graft patency. Extent of Complications Complications can be broadly divided into catastrophic events, such as death and stroke, or less serious complications, such as pulmonary, renal, or sternal wound complications. Death Mortality following CABG is reported to be between 1%-2% for elective procedures; however, it can be confounded by many factors including the urgency of the case, previous acute myocardial events, the presence of multiple comorbidities such as diabetes or chronic renal failure, or poor coronary vessels that are not amenable for grafting. 4-6 Stroke Post-operative stroke has an incidence of 1.4% to 3.8%. 2 The risk factors for this complication include increased age,

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Cardiopulmonary bypass: development of John Gibbon's heart-lung machine

Cited by 44 publications

References 35 publications

Association of Perioperative Serum Sodium Level Fluctuation and Postoperative Complications in Coronary Artery Bypass Graft Surgery

Association of Perioperative Serum Sodium Level Fluctuation and Postoperative Complications in Coronary Artery Bypass Graft Surgery

Options in extracorporeal support of multiple organ failure

Complications of Coronary Artery Bypass Grafting

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