Cardiopulmonary Hemodynamic Profile Predicts Mortality After Transcatheter Tricuspid Valve Repair in Chronic Heart Failure

Stocker, Thomas J.; Hertell, Helene; Orban, Mathias; Braun, Daniel; Rommel, Karl‐Philipp; Ruf, T.; Ong, Géraldine; Näbauer, Michael; Deseive, Simon; Fam, Neil; Bardeleben, Ralph Stephan von; Thiele, Holger; Maßberg, Steffen; Lurz, Philipp; Hausleiter, Jörg

doi:10.1016/j.jcin.2020.09.033

Cited by 93 publications

(64 citation statements)

References 27 publications

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“…Moreover, evaluation of a pulmonary haemodynamic profile further stratifies the risk of patients undergoing transcatheter intervention 42 . The risk for mortality is only moderately increased in patients with postcapillary PH compared to patients without PH 43 . In contrast, a significant precapillary contribution to PH was demonstrated to be a high-risk constellation and was associated with increased mortality after a transcatheter approach 43 .…”

Section: Figure 12 Cardioband Procedures In the Mitral Valve A) Basel...mentioning

confidence: 89%

“…The risk for mortality is only moderately increased in patients with postcapillary PH compared to patients without PH 43 . In contrast, a significant precapillary contribution to PH was demonstrated to be a high-risk constellation and was associated with increased mortality after a transcatheter approach 43 . On the basis of these findings, patients categorised into the postcapillary PH group benefit from transcatheter intervention 43 .…”

Section: Figure 12 Cardioband Procedures In the Mitral Valve A) Basel...mentioning

confidence: 89%

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Echocardiographic guidance in transcatheter structural cardiac interventions

Agricola¹,

Meucci²,

Ancona³

et al. 2022

EuroIntervention

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Catheter-based treatment of structural heart diseases (SHD) has seen tremendous advances in the past decades, thanks to the development of new devices and advances in imaging techniques. Today, we have an extensive armamentarium of imaging tools for preprocedural planning, intraprocedural guidance and follow-up of SHD. Intraprocedural guidance is based mainly on transoesophageal echocardiography; however, other imaging modalities are used as complementary or alternative techniques, each of them with its strengths and weaknesses. Thus, a multimodality imaging approach provides added values in this setting.

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Section: Figure 12 Cardioband Procedures In the Mitral Valve A) Basel...mentioning

confidence: 89%

Section: Figure 12 Cardioband Procedures In the Mitral Valve A) Basel...mentioning

confidence: 89%

Echocardiographic guidance in transcatheter structural cardiac interventions

Agricola¹,

Meucci²,

Ancona³

et al. 2022

EuroIntervention

View full text Add to dashboard Cite

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“…Importantly, estimation of pulmonary pressures using Doppler gradient may be impossible or might underestimate the severity of pulmonary hypertension in the presence of severe tricuspid regurgitation, justifying cardiac catheterization to evaluate pulmonary vascular resistances. 413…”

Section: Discussionmentioning

confidence: 99%

2021 ESC/EACTS Guidelines for the management of valvular heart disease

Vahanian¹,

Beyersdorf²,

Praz³

et al. 2022

EuroIntervention

570

581

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The ESC Guidelines represent the views of the ESC and were produced after careful consideration of the scientific and medical knowledge and the evidence available at the time of their dating. The ESC is not responsible in the event of any contradiction, discrepancy and/or ambiguity between the ESC Guidelines and any other official recommendations or guidelines issued by the relevant public health authorities, in particular in relation to good use of health care or therapeutic strategies. Health professionals are encouraged to take the ESC Guidelines fully into account when exercising their clinical judgment as well as in the determination and the implementation of preventive, diagnostic or therapeutic medical strategies. However, the ESC Guidelines do not override in any way whatsoever the individual responsibility of health professionals to make appropriate and accurate decisions in consideration of each patient's health condition and in consultation with that patient and the patient's caregiver where appropriate and/or necessary. Nor do the ESC Guidelines exempt health professionals from taking careful and full consideration of the relevant official updated recommendations or guidelines issued by the competent public health authorities in order to manage each patient's case in light of the scientifically accepted data pursuant to their respective ethical and professional obligations. It is also the health professional's responsibility to verify the applicable rules and regulations relating to drugs and medical devices at the time of prescription.

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“…Up until now, the ideal candidate seems to be a patient with FTR and partially preserved leaflets co-aptation, in the absence of significant apical valve tethering, RV dysfunction and PH ( 91 , 92 ); in case of extreme left ventricular dysfunction these devices may eventually be considered, in selected cases, only as a palliative approach, but we need randomized clinical trials to address this unmet clinical need.…”

Section: Therapeutic Optionsmentioning

confidence: 99%

Tricuspid Regurgitation in Left Ventricular Systolic Dysfunction: Marker or Target?

Margonato

Ancona

Ingallina

et al. 2021

Front. Cardiovasc. Med.

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Far from being historically considered a primary healthcare problem, tricuspid regurgitation (TR) has recently gained much attention from the scientific community. In fact, in the last years, robust evidence has emerged regarding the epidemiological impact of TR, whose prevalence seems to be similar to that of other valvulopathies, such as aortic stenosis, with an estimated up to 4% of people >75 years affected by at least moderate TR in the United States, and up to 23% among patients suffering from heart failure with reduced ejection fraction. This recurrent coexistence of left ventricular systolic dysfunction (LVSD) and TR is not surprising, considered the multiple etiologies of tricuspid valve disease. TR can complicate heart failure mostly as a functional disease, because of pulmonary hypertension (PH), subsequent to elevated left ventricular end-diastolic pressure, leading to right ventricular dilatation, and valve tethering. Moreover, the so-called “functional isolated” TR can occur, in the absence of PH, as a result of right atrial dilatation associated with atrial fibrillation, a common finding in patients with LVSD. Finally, TR can result as a iatrogenic consequence of transvalvular lead insertion, another frequent scenario in this cohort of patients. Nonetheless, despite the significant coincidence of these two conditions, their mutual relation, and the independent prognostic role of TR is still a matter of debate. Whether significant TR is just a marker for advanced left-heart disease, or a crucial potential therapeutical target, remains unclear. Aim of the authors in this review is to present an update concerning the epidemiological features and the clinical burden of TR in the context of LVSD, its prognostic value, and the potential benefit for early tricuspid intervention in patients affected by contemporary TR and LVSD.

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Cardiopulmonary Hemodynamic Profile Predicts Mortality After Transcatheter Tricuspid Valve Repair in Chronic Heart Failure

Cited by 93 publications

References 27 publications

Echocardiographic guidance in transcatheter structural cardiac interventions

Echocardiographic guidance in transcatheter structural cardiac interventions

2021 ESC/EACTS Guidelines for the management of valvular heart disease

Tricuspid Regurgitation in Left Ventricular Systolic Dysfunction: Marker or Target?

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