Cardiorenal benefits of finerenone in different races and kidney function in patients with chronic kidney disease
Pingjiang Li,
Yuying Cui,
Xiaoming Xu
et al.
Abstract:Background: Mineralocorticoid receptor plays an important pathophysiological role in cardiorenal diseases by causing inflammation and fibrosis. Mineralocorticoid receptor antagonists (MRAs) are well known in treating cardiovascular disease and diverse nephropathies. However, the first-generation MRA (spironolactone) and the second-generation MRA (eplerenone) remain underutilized because of the risk of inducing severe adverse events. As a selective non-steroidal MRA, finerenone is safer and more effective and i… Show more
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