Cardiorenal multimorbidity in hospitalized cardiology patients: The Hellenic Cardiorenal Morbidity Snapshot (HECMOS) study

Leontsinis, Ioannis; Farmakis, Dimitrios; Avramides, Dimitrios; Andrikou, Eirini; Valatsou, Angeliki; Gartzonikas, Ilias K.; Doundoulakis, Ioannis; Zarifis, Ioannis; Karpouzis, Ioannis; Kafkala, Kristalenia; Kouvelas, Nikos; Kourek, Christos; Koufou, Eleni‐Evangelia; Kochiadakis, George E.; Kifnidis, K; Liori, Sotiria; Manolis, George D.; Marketou, Maria; Moschos, Nikitas; Bampatsias, Dimitrios; Bibis, George; Bonou, Μaria; Naka, Aikaterini; Davlouros, Periklis; Ntalakouras, Ioannis; Papakonstantinou, Panteleimon E.; Pappa, Eleni; Patsilinakos, Sotirios; Plaitis, Aristeidis; Sideris, Antonios; Sideris, Skevos; Skoularigis, John; Stamatelopoulos, Kimon; Stefanou, Garyfallia; Tziakas, Dimitrios; Chatzieleftheriou, Christos; Chrysochoou, Christina; Filippatos, Gerasimos; Tsioufis, Costas; Tsioufis, Κonstantinos

doi:10.1016/j.hjc.2023.03.006

Cited by 7 publications

(2 citation statements)

References 63 publications

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“…HECMOS was a multicenter cross-sectional observational snapshot survey that investigated the contemporary trends of cardiorenal morbidity among hospitalized patients in cardiology wards across Greece on an ordinary weekday, the 3rd of March 2022 [11]. The First Cardiology Clinic of the National and Kapodistrian University of Athens (NKUA) organized it in collaboration with the 2nd and 3rd NKUA Cardiology Clinics under the auspices of INAKEN (Institute for study, research, and education of vascular, heart, brain, and kidney nosologies).…”

Section: Methodsmentioning

confidence: 99%

Anticoagulation Status and Left Atrial Appendage Occlusion Indications in Hospitalized Cardiology Patients with Atrial Fibrillation: A Hellenic Cardiorenal Morbidity Snapshot (HECMOS) Sub-Study

Tsiachris,

Papakonstantinou,

Doundoulakis

et al. 2023

Preprint

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Background and Objectives: Proper use of oral anticoagulants is crucial in the management of non-valvular atrial fibrillation (AF) patients. Left atrial appendage closure (LAAC) may be considered for stroke prevention in patients with AF and contraindications for long-term anticoagulant treatment. We aimed to assess the anticoagulation status and LAAC indications in patients with AF from HECMOS (Hellenic Cardiorenal Morbidity Snapshot) survey. Materials and Methods: HECMOS was a nationwide snapshot survey of cardiorenal morbidity in hospitalized cardiology patients. HECMOS used an electronic platform to collect demographic and clinically relevant information from all patients hospitalized on March 3, 2022, in 55 different cardiology departments. In this substudy, we included patients with known AF without mechanical prosthetic valves and moderate to severe mitral valve stenosis. Patients with prior stroke, previous major bleeding, poor adherence to anticoagulants, and end-stage renal disease were considered candidates for LAAC. Results: Two hundred fifty-six patients (mean age 76.6±11.7, 148 males) were included in our analysis. Most of them (n=159; 62%) suffered from persistent AF. Mean CHA2DS2-VASc score was 4.28±1.7, while mean HAS-BLED score was 1.47±0.9. Three out of 3 patients with a CHA2DS2-VASc 0 or 1 (female) received improperly anticoagulants. Sixteen out of 18 patients with a CHA2DS2-VASc 1 or 2 (female) received anticoagulants. Thirty-three out of 235 patients with a CHA2DS2-VASc &gt; 1 or 2 (for female) did not receive improperly anticoagulants. Among 221 under anticoagulant therapy, 191 (86.4%) received non-vitamin K antagonist oral anticoagulants (NOACs) and 30 (13.6%) received vitamin K antagonists. Relative indications for LAAC were present in 64 patients with NVAF (60 had only one risk factor and 2 had two concurrent risk factors). In detail, 36 had a prior stroke, 17 patients had a history of major bleeding, 15 patients reported poor or no adherence to the anticoagulant therapy and 5 had eGFR&lt; 15 ml/min/1.73m2. Moreover, 33 had a HAS-BLED score ≥3. No LAAC treatment was recorded. Conclusions: Anticoagulation status was nearly optimal in a high thromboembolic risk population of cardiology patients, mainly treated with NOACs. One out of four AF patients should be screened for LAAC.

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Section: Methodsmentioning

confidence: 99%

Anticoagulation Status and Left Atrial Appendage Occlusion Indications in Hospitalized Cardiology Patients with Atrial Fibrillation: A Hellenic Cardiorenal Morbidity Snapshot (HECMOS) Sub-Study

Tsiachris,

Papakonstantinou,

Doundoulakis

et al. 2023

Preprint

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“…Detailed descriptions of the study population, design and results have been reported. Briefly, the HECMOS study sought to investigate the contemporary trends in cardiorenal morbidity among hospitalized patients in cardiology wards across Greece on an ordinary weekday, 3 March 2022 [13]. The First Cardiology Clinic of the National and Kapodistrian University of Athens (NKUA) organized the study in collaboration with the Second and Third NKUA Cardiology Clinics under the auspices of INAKEN (the Institute for Study, Research, and Education on Vascular, Heart, Brain, and Kidney Disease).…”

Section: Methodsmentioning

confidence: 99%

Anticoagulation Status and Left Atrial Appendage Occlusion Indications in Hospitalized Cardiology Patients with Atrial Fibrillation: A Hellenic Cardiorenal Morbidity Snapshot (HECMOS) Sub-Study

Tsiachris,

Papakonstantinou,

Doundoulakis

et al. 2023

Medicina

Self Cite

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Background and Objectives: The proper use of oral anticoagulants is crucial in the management of non-valvular atrial fibrillation (AF) patients. Left atrial appendage closure (LAAC) may be considered for stroke prevention in patients with AF and contraindications for long-term anticoagulant treatment. We aimed to assess anticoagulation status and LAAC indications in patients with AF from the HECMOS (Hellenic Cardiorenal Morbidity Snapshot) survey. Materials and Methods: The HECMOS was a nationwide snapshot survey of cardiorenal morbidity in hospitalized cardiology patients. HECMOS used an electronic platform to collect demographic and clinically relevant information from all patients hospitalized on 3 March 2022 in 55 different cardiology departments. In this substudy, we included patients with known AF without mechanical prosthetic valves or moderate-to-severe mitral valve stenosis. Patients with prior stroke, previous major bleeding, poor adherence to anticoagulants, and end-stage renal disease were considered candidates for LAAC. Results: Two hundred fifty-six patients (mean age 76.6 ± 11.7, 148 males) were included in our analysis. Most of them (n = 159; 62%) suffered from persistent AF. The mean CHA2DS2-VASc score was 4.28 ± 1.7, while the mean HAS-BLED score was 1.47 ± 0.9. Three out of three patients with a a CHA2DS2-VASc score of 0 or 1 (female) were inappropriately anticoagulated. Sixteen out of eighteen patients with a CHA2DS2-VASc score 1 or 2 (if female) received anticoagulants. Thirty-one out of two hundred thirty-five patients with a CHA2DS2-VASc score > 1 or 2 (if female) were inappropriately not anticoagulated. Relative indications for LAAC were present in 68 patients with NVAF (63 had only one risk factor and 5 had two concurrent risk factors). In detail, 36 had a prior stroke, 17 patients had a history of major bleeding, 15 patients reported poor or no adherence to the anticoagulant therapy and 5 had an eGFR value < 15 mL/min/1.73 m2 for a total of 73 risk factors. Moreover, 33 had a HAS-BLED score ≥ 3. No LAAC treatment was recorded. Conclusions: Anticoagulation status was nearly optimal in a high-thromboembolic-risk population of cardiology patients who were mainly treated using NOACs. One out of four AF patients should be screened for LAAC.

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Resistant Hypertension and Related Outcomes in a Cohort of Patients with Cardiorenal Multimorbidity Hospitalized in an Internal Medicine Ward

Gigante,

Cianci,

Brigato

et al. 2023

High Blood Press Cardiovasc Prev

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Cardiorenal multimorbidity in hospitalized cardiology patients: The Hellenic Cardiorenal Morbidity Snapshot (HECMOS) study

Cited by 7 publications

References 63 publications

Anticoagulation Status and Left Atrial Appendage Occlusion Indications in Hospitalized Cardiology Patients with Atrial Fibrillation: A Hellenic Cardiorenal Morbidity Snapshot (HECMOS) Sub-Study

Anticoagulation Status and Left Atrial Appendage Occlusion Indications in Hospitalized Cardiology Patients with Atrial Fibrillation: A Hellenic Cardiorenal Morbidity Snapshot (HECMOS) Sub-Study

Anticoagulation Status and Left Atrial Appendage Occlusion Indications in Hospitalized Cardiology Patients with Atrial Fibrillation: A Hellenic Cardiorenal Morbidity Snapshot (HECMOS) Sub-Study

Resistant Hypertension and Related Outcomes in a Cohort of Patients with Cardiorenal Multimorbidity Hospitalized in an Internal Medicine Ward

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