Cardiorespiratory Fitness After Open Repair for Acute Type A Aortic Dissection – A Prospective Study

Norton, Elizabeth L.; Wu, Kuan-Han H; Rubenfire, Melvyn; Fink, Samantha; Sitzmann, Jacob; Hobbs, Reilly D.; Saberi, Sara; Willer, Cristen J.; Yang, Bo; Hornsby, Whitney E.

doi:10.1053/j.semtcvs.2021.05.017

Cited by 11 publications

(21 citation statements)

References 37 publications

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“…One study utilised the EQ5D scale [ 22 ]. One utilised the PROMIS questionnaire [ 27 ]. Studies assessed other parameters of well-being including VO2 max, sexual function, post traumatic stress disorder (PTSD) scales or derived their own HR-QOL questionnaire [ 13 , 21 , 23 , 24 , 27 , 29 ].…”

Section: Resultsmentioning

confidence: 99%

“…Seven studies reported the change on HR-QOL measures of patients over time [ 14 , 16 , 23 – 25 , 27 , 29 ]. Four studies reported the change of HR-QOL preoperatively (prior to the ATAAD) and post operatively [ 16 , 23 , 24 , 29 ].…”

Section: Resultsmentioning

confidence: 99%

“…Four studies reported the change of HR-QOL preoperatively (prior to the ATAAD) and post operatively [ 16 , 23 , 24 , 29 ]. Three of the included studies followed patients purely over the postoperative period [ 14 , 25 , 27 ]. Five studies reported a worse of HR-QOL over time [ 14 , 16 , 24 , 27 , 29 ].…”

Section: Resultsmentioning

confidence: 99%

“…Three of the included studies followed patients purely over the postoperative period [ 14 , 25 , 27 ]. Five studies reported a worse of HR-QOL over time [ 14 , 16 , 24 , 27 , 29 ]. One study noted that at best, HR-QOL did not demonstrate significant attrition over time postoperatively [ 25 ].…”

Section: Resultsmentioning

confidence: 99%

“…Within this, there was still variability with reporting of SF domains, with some papers utilizing MCS and PCS scores whereas others reporting individual domains. One of the included studies utilised the EQ-5D scale [ 22 ] whilst another utilised PROMIS [ 27 ]. Three included studies utilised a non-standardised HR-QOL outcomes, which makes direct comparison to standardised cohorts unattenable [ 23 , 24 , 29 ].…”

Section: Discussionmentioning

confidence: 99%

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Quality of life following surgical repair of acute type A aortic dissection: a systematic review

Eranki

Wilson-Smith

Williams

et al. 2022

J Cardiothorac Surg

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Background The outcomes of surgery for acute Stanford Type A aortic dissection (ATAAD) extend beyond mortality and morbidity. The aim of this systematic review was to summarise the literature surrounding health related quality of life (HR-QOL) following ATAAD, compare the outcomes to the standardised population, and to assess the impact of advanced age on HRQOL outcomes following surgery. Methods A systematic review of studies after January 2000 was performed to identify HR-QOL in patients following surgery for ATAAD. Electronic searches of three databases were performed and clinical studies extracted by two independent reviewers. Strict inclusion and exclusion criteria were applied. Quality appraisal was conducted utilizing predefined criteria on pilot forms. HR-QOL results were synthesized through a narrative review of included studies. Results There was significant attrition in HR-QOL of patients following surgery for ATAAD. Outcomes fared worse when compared to an age adjusted normative population. Of note, elderly patients were physically vulnerable, whereas younger populations may be more mentally vulnerable to postoperative sequalae. The included studies were quite heterogeneous in their study designs, methods, HR-QOL measures reported and follow up time-frames which limited direct comparison between studies. Conclusion HR-QOL outcomes are adversely affected when compared to preoperative status and physical health demonstrates significant attrition over time. HR-QOL outcomes are worse off when compared to an age matched general population. In terms of age, advancing age is associated with worse physical component scores but emotional health may fare better than younger patients.

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