Cardiorespiratory Fitness and Obstructive Sleep Apnea Syndrome in Morbidly Obese Patients

Vanhecke, Thomas E.; Franklin, Barry A.; Zalesin, Kerstyn C.; Sangal, R. Bart; deJong, Adam; Agrawal, Varun; McCullough, Peter A.

doi:10.1378/chest.08-0567

Cited by 65 publications

(77 citation statements)

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“…Furthermore, only one study has included CPET measurements obtained A delayed heart rate (HR) recovery after CPET is considered a predictor of overall mortality (16). Some studies have shown that patients with OSA have an ttenuated HR recovery that is dependent on OSA severity (3,5,11,17). A possible mechanism involves reduced parasympathetic activity, which is observed in patients with OSA during the recovery phase of exercise (11).…”

Section: Study Subjectsmentioning

confidence: 99%

“…A possible mechanism involves reduced parasympathetic activity, which is observed in patients with OSA during the recovery phase of exercise (11). However, HR recovery in patients with A has primarily been analysed in men because previous studies have included only a small number of women (3,11,17). This bias is of particular importance, given HR recovery might be decreased in women compared with men in some populations, such as those fected with heart disease (18).…”

Section: Study Subjectsmentioning

confidence: 99%

“…A person's sex also has an influence on exercise capacity, which could be at least 20%-40% lower in women than in men (15). These variables have not always been considered, however, when interpreting the results of studies that have evaluated exercise capacity in patients with OSA (2)(3)(4)(5)(6)(7)(8)(9)(10)12). Moreover, these reports have included only a small number of women; therefore, their results might not extend to this population.…”

Section: Introductionmentioning

confidence: 99%

“…Moreover, these reports have included only a small number of women; therefore, their results might not extend to this population. Furthe one study has included CPET measurements obtained from subjects with morbid obesity (3).…”

Section: Introductionmentioning

confidence: 99%

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Exercise capacity and heart rate recovery response to exercise in morbidly obese female patients with obstructive sleep apnoea syndrome.

et al. 2017

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INTRODUCTION:To study exercise capacity and heart rate (HR) recovery after peak exercise in morbidly obese female patients with obstructive sleep apnoea (OSA). METHODS:Twenty-four morbidly obese female patients (36.17 ± 9.20 years and 45.20 ± 5.41 kg.m diagnosed with OSA underwent cardiopulmonary exercise testing (CPET) for assessment of peak oxygen uptake (V'O2) and heart rate (HR) recovery at 30, 60 a index [AHI] <15 h-1) and moderate-to-severe (AHI RESULTS: For the entire study population, peak V'O2 was 15.58 ± 2.44 ml.min were found between moderate-to-severe and mild OSA (16.11 ± 2.37 vs. 15.19 ± 2.50 ml.min respectively). HR recovery registered at any time after the peak workload also did not differ between both groups. Nonetheless, the percentage of HR decrease at 90 seconds in the patients with moderate-to-severe OSA (p=.073), and it was negatively correlated with the oxygen desaturation index (r =-0.679, p=.044). CONCLUSION:Exercise capacity is not different bet Nevertheless, patients with moderatethose with milder OSA. Finally, the oxygen desaturation index is related to this slower chron Keywords: Obstructive sleep apnoea, Exercise test, Female, Heart rate, Obesity. Received March 20, 2017; Accepted May 11, 2017 Copyright: © 2017 Authors. This is an open License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and sourc credited. Editor: Javier Jareño Cite as: Carpio C., Santiago A., Gómez-Mendieta M., Caballero P., Martín capacity and heart rate recovery response to exercise in morbidly obese female patients with obstructive sleep apnoea syndrom IBJ Plus 2017 1(1):e0004. Funding: The author(s) declared that no grants were involved in supporting this work. To study exercise capacity and heart rate (HR) recovery after peak exercise in morbidly obese female patients with obstructive sleep apnoea (OSA).four morbidly obese female patients (36.17 ± 9.20 years and 45.20 ± 5.41 kg.m diagnosed with OSA underwent cardiopulmonary exercise testing (CPET) for assessment of peak oxygen uptake (V'O2) and heart rate (HR) recovery at 30, 60 and 90 seconds. Comparisons were made between mild (apnoea severe (AHI ≥15 h-1) OSA.For the entire study population, peak V'O2 was 15.58 ± 2.44 ml.min-1.kg-1. No differences in peak V'O2 severe and mild OSA (16.11 ± 2.37 vs. 15.19 ± 2.50 ml.min respectively). HR recovery registered at any time after the peak workload also did not differ between both groups. Nonetheless, the percentage of HR decrease at 90 seconds of recovery time was almost statistically significantly lower severe OSA (p=.073), and it was negatively correlated with the oxygen desaturation Exercise capacity is not different between patients with mild and moderate -to-severe OSA tend to have a slower HR recovery response to exercise than those with milder OSA. Finally, the oxygen desaturation index is related to this slower chronotropic response.Obstructive sleep apnoea, Exercise test, Female, Heart rate, Obesity.May 11, 2017; Published May 23, 2017...

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Section: Study Subjectsmentioning

confidence: 99%

Section: Study Subjectsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Exercise capacity and heart rate recovery response to exercise in morbidly obese female patients with obstructive sleep apnoea syndrome.

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“…In a cohort of morbidly obese patients, Vanhecke et al [7] found that those with OSA had slower HRR than those without. Similarly, Hargens et al [8] demonstrated that overweight young men with OSA had significantly slower HRR than men with similar body mass index but without OSA and men with normal weight and without OSA.…”

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confidence: 99%

Heart rate recovery in obstructive sleep apnea: scientific toy or clinical tool?

Maeder

2011

Sleep Breath

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Influence of Sleep-Disordered Breathing on Quality of Life and Exercise Capacity in Lung Transplant Recipients

Kruse

Kleibrink

Rabis

et al. 2019

Advances in Pulmonary Medicine: Research and Innovations

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Cardiorespiratory Fitness and Obstructive Sleep Apnea Syndrome in Morbidly Obese Patients

Cited by 65 publications

References 34 publications

Exercise capacity and heart rate recovery response to exercise in morbidly obese female patients with obstructive sleep apnoea syndrome.

Exercise capacity and heart rate recovery response to exercise in morbidly obese female patients with obstructive sleep apnoea syndrome.

Heart rate recovery in obstructive sleep apnea: scientific toy or clinical tool?

Influence of Sleep-Disordered Breathing on Quality of Life and Exercise Capacity in Lung Transplant Recipients

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