Cardiorespiratory fitness, muscle fitness, and physical activity in children with long QT syndrome: A prospective controlled study

Souilla, Luc; Avesani, Martina; Boisson, A; Requirand, Anne; Matecki, Stéfan; Vincenti, Marie; Werner, Oscar; Villeon, Grégoire De La; Pommier, Victor; Pasquié, Jean‐Luc; Guillaumont, Sophie; Amédro, Pascal

doi:10.3389/fcvm.2022.1081106

Cited by 4 publications

(2 citation statements)

References 63 publications

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“… 62 Furthermore, lower cardiorespiratory and muscular fitness in children with multimorbidity could further hinder their engagement in physical activity. 63 , 64 …”

Section: Discussionmentioning

confidence: 99%

Childhood and adolescence physical activity and multimorbidity later in life: A systematic review

Souilla,

Larsen,

Juhl

et al. 2024

Journal of Multimorbidity and Comorbidity

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Background No systematic summary exists on childhood physical activity and later-life multimorbidity risks. We primarily investigated the association of physical activity in childhood and adolescence and the development of multimorbidity in adulthood. Secondarily, we examined whether physical activity level differ in children and adolescents with and without multimorbidity and whether there is a cross-sectional association between physical activity and multimorbidity. Methods Following Cochrane Handbook guidelines and adhering to PRISMA recommendations, we included cross-sectional, case-control and longitudinal studies that investigated the association between physical activity in children and adolescents and development of multimorbidity. Results were summarized narratively and we assessed the certainty of the evidence using the GRADE approach. The protocol was registered in PROSPERO, CRD42023407063. Results Of 9064 studies identified, 11 were included in 13 papers. Longitudinals studies suggested that being physically active in childhood and adolescence was associated with a lower risk of multimorbidity in adulthood. Three out of five studies reported lower physical activity level in children and adolescents with multimorbidity compared to those without, and two did not find a between-group difference. Cross-sectional evidence on the association between multimorbidity and lower physical activity was uncertain. Overall, the evidence certainty for all outcomes was considered low due to the indirectness and inconsistency in findings. Conclusions Childhood and adolescence physical activity appeared to be linked with a reduced risk of later-life multimorbidity but the certainty of the evidence is low. These results support the promotion of physical activity during childhood and adolescence.

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“… 62 Furthermore, lower cardiorespiratory and muscular fitness in children with multimorbidity could further hinder their engagement in physical activity. 63 , 64 …”

Section: Discussionmentioning

confidence: 99%

Childhood and adolescence physical activity and multimorbidity later in life: A systematic review

Souilla,

Larsen,

Juhl

et al. 2024

Journal of Multimorbidity and Comorbidity

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“…The situation is complicated when climate change acts as both a cause or consequence to greater physical inactivity (21) which currently affects >80% of adolescents globally (13). Children with heart conditions already present with lower cardiorespiratory fitness compared to healthy controls (3,30), and this decline remains so over time (9). Higher fitness elicits efficient heat balance since fitter people sweat more and can tolerate higher core temperatures (24) than unfit people.…”

Section: Practical Implications Of Exercising In the Heatmentioning

confidence: 99%

Children With Cardiac Disease and Heat Exposure: Catastrophic Converging Consequences?

Souilla,

Amedro,

Morrison

2024

Pediatric Exercise Science

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The detrimental impact of extreme heat exposure on the health and well-being of children is widely acknowledged. The direct and indirect effects of climate change have led to an increased risk of certain cardiovascular events which may be particularly harmful to children who are born with, or develop, heart disease. Purpose: To highlight the worrying paucity of investigative research aimed at differentiating how higher ambient temperatures further tax an already compromised cardiovascular system in children. Methods: This commentary describes basic thermoregulatory concepts relevant to the healthy pediatric population and summarizes common heart diseases observed in this population. Results: We describe how heat stress and exercise are important factors clinicians should more readily consider when treating children with heart disease. Countermeasures to physical inactivity are suggested for children, parents, clinicians, and policymakers to consider. Conclusions: As sudden, excessive heat exposures continue to impact our rapidly warming world, vulnerable populations like children with underlying heart conditions are at greater heat health risk, especially when coupled with the negative physical activity and fitness trends observed worldwide.

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Early hybrid cardiac rehabilitation in congenital heart disease: the QUALIREHAB trial

Amedro,

Gavotto,

Huguet

et al. 2024

European Heart Journal

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Background and Aims Cardiopulmonary fitness in congenital heart disease (CHD) decreases faster than in the general population resulting in impaired health-related quality of life (HRQoL). As the standard of care seems insufficient to encourage and maintain fitness, an early hybrid cardiac rehabilitation programme could improve HRQoL in CHD. Methods The QUALIREHAB multicentre, randomized, controlled trial evaluated and implemented a 12-week centre- and home-based hybrid cardiac rehabilitation programme, including multidisciplinary care and physical activity sessions. Adolescent and young adult CHD patients with impaired cardiopulmonary fitness were randomly assigned to either the intervention (i.e. cardiac rehabilitation) or the standard of care. The primary outcome was the change in HRQoL from baseline to 12-month follow-up in an intention-to-treat analysis. The secondary outcomes were the change in cardiovascular parameters, cardiopulmonary fitness, and mental health. Results The expected number of 142 patients was enroled in the study (mean age 17.4 ± 3.4 years, 52% female). Patients assigned to the intervention had a significant positive change in HRQoL total score [mean difference 3.8; 95% confidence interval (CI) 0.2; 7.3; P = .038; effect size 0.34], body mass index [mean difference −0.7 kg/m2 (95% CI −1.3; −0.1); P = .022; effect size 0.41], level of physical activity [mean difference 2.5 (95% CI 0.1; 5); P = .044; effect size 0.39], and disease knowledge [mean difference 2.7 (95% CI 0.8; 4.6); P = .007; effect size 0.51]. The per-protocol analysis confirmed these results with a higher magnitude of differences. Acceptability, safety, and short-time effect of the intervention were good to excellent. Conclusions This early hybrid cardiac rehabilitation programme improved HRQoL, body mass index, physical activity, and disease knowledge, in youth with CHD, opening up the possibility for the QUALIREHAB programme to be rolled out to the adult population of CHD and non-congenital cardiac disease.

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Cardiorespiratory fitness, muscle fitness, and physical activity in children with long QT syndrome: A prospective controlled study

Cited by 4 publications

References 63 publications

Childhood and adolescence physical activity and multimorbidity later in life: A systematic review

Childhood and adolescence physical activity and multimorbidity later in life: A systematic review

Children With Cardiac Disease and Heat Exposure: Catastrophic Converging Consequences?

Early hybrid cardiac rehabilitation in congenital heart disease: the QUALIREHAB trial

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