Cardiotrophin-1: A new predictor of atrial fibrillation relapses after successful cardioversion

Altun, İbrahim; Pamukçu, Burak; Yıldız, Cenk Eray; Arkaya, Selda Can; Güz, Göksel; Yılmaz, Akar; Bilge, Ahmet Kaya; Türkoğlu, Ümit; Adalet, Kâmil

doi:10.17305/bjbms.2015.503

Cited by 10 publications

(9 citation statements)

References 29 publications

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“…In our study, especially in patients with STEMI, CT-1 levels increased more than the other ACS groups, supporting its myocardial protective effects in terms of prognosis. Altun et al found a positive correlation between CT-1 levels and recurrence of AF after cardioversion in 32 patients with AF (19). In our study, AF was detected in 4 patients; but CT-1 levels were not different between groups with and without AF.…”

Section: Discussioncontrasting

confidence: 57%

The Correlation between Cardiac Enzymes and Cardiotrophin-1 Levels in Patients with Acute Coronary Syndrome

Polat¹,

Aydınlar²,

Caliskan³

et al. 2021

International Journal of Cardiovascular Sciences

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Cardiovascular diseases are the major causes of mortality and morbidity, especially among the aging population. 1 Studies have reported that one out of every five deaths in the United States is caused by coronary atherosclerosis. 2 It is expected that CAD will take the number 1 place in the list of 2020 causes of death prepared by the World Health Organization 3 Similar studies examining coronary artery disease (CAD) associated mortality in European countries (an average of 30 countries) report that the aforementioned

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Section: Discussioncontrasting

confidence: 57%

The Correlation between Cardiac Enzymes and Cardiotrophin-1 Levels in Patients with Acute Coronary Syndrome

Polat¹,

Aydınlar²,

Caliskan³

et al. 2021

International Journal of Cardiovascular Sciences

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“…This is the first study to report that increased EFT thickness is associated with cardioversion failure. The number of novel indices including recurrent AF‐related echocardiographic parameters, such as left atrium volume index, atrial emptying fraction, and biomarkers such as cardiotroponin‐1 and NT ProBNP are increasingly used . These predictors may be valuable when making decisions about rhythm control in clinical practice and during ECV planning.…”

Section: Discussionmentioning

confidence: 99%

Epicardial fat thickness: A new predictor of successful electrical cardioversion and atrial fibrillation recurrence

et al. 2018

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Objective In recent years, epicardial fat tissue (EFT) has been found to be strongly associated with the development of atrial fibrillation (AF) and post‐ablation long‐term recurrence. The current study investigated the procedural success rate of electrical cardioversion (ECV) and potential predictors of treatment failure in patients with nonvalvular persistent AF. Methods A total of 262 nonvalvular persistent AF patients who were scheduled for elective ECV were included in this prospective study. Routine transthoracic echocardiography was performed before the procedure and EFT thickness was measured. The presence of left atrial appendage thrombus was evaluated by transesophageal echocardiography. The patients were followed up for 6 months to examine any recurrence after ECV. Results The success rate of ECV was 85% and the recurrence rate was 35% during the 6‐month follow‐up period. The mean EFT thickness was 8.67 ± 1.2 mm in the persistent AF group with unsuccessful ECV and 6.81 ± 0.8 in the patients in whom sinus rhythm (SR) was maintained, the EFT was significantly thicker in the AF group (P = 0.001). EFT (P = 0.001) and left ventricular end‐diastolic diameters (LVEDD) (P = 0.001) were significantly different between those who had maintained SR and those with recurrent AF during the 6‐month follow‐up period after ECV. In the multiple logistic regression analysis, LVEDD (odds ratio [OR]: 1.320 (1.023–1.703 95% confidence interval [CI]), P = 0.032)] and EFT [OR: 3.029 (1.013–9.055 95% CI), P = 0.047)] were identified as independent predictors of successful ECV. Conclusion Epicardial fat tissue thickness can be effectively used for the prediction of successful ECV and AF recurrence during follow‐up in AF patients.

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“…The receiver operating characteristic (ROC) curve analysis of platelet-to-lymphocyte ratio for predicting atrial fibrillation recurrence and different novel indices such as echocardiographically determined left atrial volume index and atrial emptying fraction, and biomarkers including cardiotroponin-1 and N-terminal pro-brain natriuretic peptide (NT-proBNP) are increasing (Altun et al, 2015;Andersson, Rosenqvist, Tornvall, & Boman, 2015;Luong et al, 2016;Toufan, Kazemi, & Molazadeh, 2017). These predictors may serve as a valuable tool when determining the rhythm control in clinical practice and when planning ECV; however, less expensive and more practical measures are required to predict recurrences.…”

Section: Discussionmentioning

confidence: 99%

Usefulness of platelet to lymphocyte ratio for predicting recurrence of atrial fibrillation after direct current cardioversion

Dereli

Bayramoğlu

Yontar

2018

Noninvasive Electrocardiol

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Objective: Atrial fibrillation (AF) is the most common cardiac rhythm disorder with the associated risks of stroke and mortality. The usefulness of platelet to lymphocyte ratio (PLR), a recently described inflammatory marker, in predicting adverse cardiovascular events has been demonstrated in several studies. In the current study, we investigated the role of PLR in predicting recurrence after successful electrical cardioversion (ECV) in patients with non-valvular persistent AF.Methods: A total of 287 patients with non-valvular persistent AF achieving restoration of the sinus rhythm after successful ECV were included in this study. At study entry, complete blood count, routine biochemistry tests, and transthoracic echocardiography (TTE) were performed routinely in all subjects. Patients were followed up for 6 months following the procedure and comparisons were performed between patients who recurred and who maintained the sinus rhythm (SR).Results: At 6 months of follow-up, AF recurred in 108 patients, corresponding to a recurrence rate of 39%. Mean PLR values in the "AF recurrence group" (mean age 57.4 ± 12.0 years, 47.6% [n = 80] female) and in "SR maintenance" group (mean age 65.0 ± 9.4 years, 55.6%[n = 60] female) were 184.8 ± 44.2 and 103.3 ± 44.2, respectively, with a significant difference between the two groups (p < 0.001). In multiple regression analyses, PLR emerged as a risk factor associated with AF recurrence during the 6-month follow-up period after successful ECV (odds ratio [OR]: 3.029 (1.013-9.055 95% confidence interval [CI]), p = 0.047).When a cutoff value of 147 was used, the sensitivity and specificity of PLR for predicting AF recurrence were 83.3% and 84.5%, respectively. Conclusion:Elevated PLR is a marker of increased inflammation and may serve as a practical and inexpensive predictor for recurrence during 6 months of follow-up in patients with non-valvular persistent AF who had restoration of the sinus rhythm after successful ECV.

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Cardiotrophin-1: A new predictor of atrial fibrillation relapses after successful cardioversion

Cited by 10 publications

References 29 publications

The Correlation between Cardiac Enzymes and Cardiotrophin-1 Levels in Patients with Acute Coronary Syndrome

The Correlation between Cardiac Enzymes and Cardiotrophin-1 Levels in Patients with Acute Coronary Syndrome

Epicardial fat thickness: A new predictor of successful electrical cardioversion and atrial fibrillation recurrence

Usefulness of platelet to lymphocyte ratio for predicting recurrence of atrial fibrillation after direct current cardioversion

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