Background: Endotracheal intubation has become the mainstay of modern anaesthesia. Stimulation of upper respiratory tract during tracheal intubation under general anaesthesia causes activation of sympatho-adrenal system and results in increased serum catecholamines. Aims and Objectives: To identify and compare the hemodynamic responses contributed by each stage of nasotracheal with that of orotracheal intubation. Material and Methods: About 125 patients in the age group 18-50 years, ASA physical status I-II of either sex, scheduled to undergo various elective surgical procedures requiring nasotracheal or orotracheal intubation were evaluated in the present study.After 4 minutes of ventilation, patients requiring nasal intubation (n=75) were allocated to three groups-nasopharyngeal intubation group (NPI), nasopharyngeal intubation with laryngoscopy group (NPIL) and nasotracheal intubation group (NTI). Those requiring oral intubation (n=50) were allocated to two groups namely-laryngoscopy only group (L) and laryngoscopy followed by orotracheal intubation group (OTI). Haemodynamic parameters like heart rate and blood pressure, SpO2, ECG, ETCO 2 were monitored continuously and data were recorded before induction, just after induction and after intubation at one minute interval for five minutes. Results: The pre-induction and pre-procedure values of systolic, diastolic and mean arterial pressures and also heart rate were similar in each group (P<0.05). Induction of anaesthesia caused a significant decrease in systolic, diastolic and mean arterial pressures in all groups compared to their pre-induction values (P<0.0012). Our study showed that systolic, diastolic and mean arterial pressures were significantly increased after intubation procedures in all the five groups compared to pre-procedure values. Conclusion: All the procedures evoked cardiovascular responses characterized by increases in heart rate and blood pressure. NTI produced a significant rise in blood pressure.