Cardiovascular complications after COVID-19 in chronic kidney disease, dialysis and kidney transplant patients

Loutradis, Charalampos; Pitoulias, Apostolos G.; Pagkopoulou, Eleni; Pitoulias, Georgios A.

doi:10.1007/s11255-021-03059-3

Cited by 6 publications

(3 citation statements)

References 103 publications

(143 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Vascular imaging studies have documented an augmented prevalence of carotid artery atherosclerosis among dialysis subjects compared to those with normal renal function, consistent with the well-established association between renal impairment and generalized atherosclerotic vascular alteration. Although associated with a shorter prognosis, the long-term cardiovascular consequences of COVID-19 survivors remain largely unclear [ 39 , 40 , 41 ].…”

Section: Discussionmentioning

confidence: 99%

Early Detection of Inflammation and Malnutrition and Prediction of Acute Events in Hemodialysis Patients through PINI (Prognostic Inflammatory and Nutritional Index)

Cordos,

Martu,

Vlad

et al. 2024

Diagnostics

View full text Add to dashboard Cite

Protein-energy wasting and inflammation are major risk factors for complications in hemodialysis patients. As these risk factors are triggered by a pro-inflammatory state, oxidative stress and hemodynamic dysfunction, which overlap in hemodialyzed subjects, we aimed to assess the efficacy of a cost-effective and straightforward screening tool, the Prognostic Inflammatory and Nutritional Index (PINI), in regularly screening maintenance hemodialysis (MHD) patients, to detect early signs of inflammation and malnutrition. A 12-month follow-up was carried out on a cohort of 102 adult patients undergoing maintenance dialysis, during which the Prognostic Inflammatory and Nutritional Index (PINI) was calculated using the formula alpha1-Acid Glycoprotein (AGP) × C-reactive protein (CRP)/albumin (ALB) × transthyretin (TTR). A PINI score < 1 was considered normal. The patients were stratified based on their PINI score: 66 patients (64.70%) had a normal score, below 1, while 36 patients (35.30%) had a PINI score ≥ 1. Despite the absence of clinical evidence of inflammation at enrollment, the latter group exhibited higher levels of CRP. During the follow-up period, all patients with a PINI score ≥ 1 experienced at least one acute event, compared to only 6% of patients with a normal PINI score, which presented COVID-19 infection as an acute event. The evaluation of the PINI can effectively identify the silent malnutrition–inflammation syndrome and predict the risk of acute events. This straightforward test appears to be a rapid tool that is independent of the examiner’s experience and subjectivity, thereby potentially reducing hospitalization costs.

show abstract

Section: Discussionmentioning

confidence: 99%

Early Detection of Inflammation and Malnutrition and Prediction of Acute Events in Hemodialysis Patients through PINI (Prognostic Inflammatory and Nutritional Index)

Cordos,

Martu,

Vlad

et al. 2024

Diagnostics

View full text Add to dashboard Cite

show abstract

“…Compared with general population, the patients with chronic kidney disease have a higher risk for cardiovascular disease, severe COVID‐19 infection, COVID‐19‐related mortality, and cardiovascular complications after COVID‐19 infection recovery [7, 8].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the changes in electrocardiographic ventricular repolarization parameters after COVID‐19 recovery in hemodialysis patients

Yazıcı

Güney

2023

Ther Apher Dial

View full text Add to dashboard Cite

IntroductionCoronavirus disease‐2019 (COVID‐19) has cardiac manifestations. Data about electrocardiogram (ECG) changes after COVID‐19 recovery is limited in hemodialysis patients. We aimed to investigate the changes in ventricular repolarization parameters after COVID‐19 recovery in hemodialysis patients.MethodsFifty‐five hemodialysis patients who recovered from COVID‐19 infection were included. QT interval, Tp‐e interval, corrected QT (QTc), QTc dispersion, and Tp‐e dispersion values were determined on the patients' ECGs, taken before COVID‐19 and at least 1 month after recovery. The patients' data before COVID‐19 infection and after recovery were compared.ResultsIt was found that longest QTc (QTcmax) and QTc dispersion values after recovery were prolonged compared with pre‐infection period (427 ± 28 ms vs. 455 ± 26 ms, p = 0.000 and 39 ± 16 ms vs. 65 ± 20 ms, p = 0.000).ConclusionIn our hemodialysis patients, ventricular repolarization parameters increased after COVİD‐19 recovery. In hemodialysis patients, already predisposed to arrhythmic deaths, arrhythmia risk after COVİD‐19 recovery may become more pronounced.

show abstract

“…Diagnosis and care of renal disease in developing countries is fraught with obstacles. The COVID-19 pandemic made some tasks even more difficult, for example outpatient kidney care during 2020 in Panama, due to disruption of the usual network of care, and the reassignment of health personnel to COVID rooms or vaccination posts [ 1 ].…”

mentioning

confidence: 99%

Overcoming obstacles in Panama to starting a renal biopsy program in a rural area during the COVID-19 pandemic

Courville

Milord

Cerrud³

et al. 2022

J Nephrol

View full text Add to dashboard Cite

Due to the many implemented restrictions, the SARS-CoV-2 pandemic has rendered some tasks more difficult, for instance, the evaluation of outpatients. Panama’s tertiary care hospital for kidney biopsy referral was transformed into a COVID-only hospital in order to assist the large number of COVID-19 patients. In order to face the impossibility of following patients with nephrotic or nephritic syndrome, a biopsy program was implemented in a southern province in Panama. Thirty kidney biopsies were carried out over a 1-year period. This experience shows that kidney biopsy programs, that are usually run only in large referral centers, can also be implemented in small nephrology centers, allowing to obtain accurate diagnoses and to guide correct treatment.

show abstract

Cardiovascular complications after COVID-19 in chronic kidney disease, dialysis and kidney transplant patients

Cited by 6 publications

References 103 publications

Early Detection of Inflammation and Malnutrition and Prediction of Acute Events in Hemodialysis Patients through PINI (Prognostic Inflammatory and Nutritional Index)

Early Detection of Inflammation and Malnutrition and Prediction of Acute Events in Hemodialysis Patients through PINI (Prognostic Inflammatory and Nutritional Index)

Evaluation of the changes in electrocardiographic ventricular repolarization parameters after COVID‐19 recovery in hemodialysis patients

Overcoming obstacles in Panama to starting a renal biopsy program in a rural area during the COVID-19 pandemic

Contact Info

Product

Resources

About