Cardiovascular disease among people with drug use disorders

Thylstrup, Birgitte; Clausen, Thomas; Hesse, Morten

doi:10.1007/s00038-015-0698-3

Cited by 33 publications

(27 citation statements)

References 34 publications

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“…Some of the main somatic problems previously reported for this population in Norway have been hepatitis C, liver failure, cancer, kidney and lung disease [11,12]. A recent Danish study reported an earlier onset of cardiovascular disease among hospitalized drug users compared to the general population [13], and it is likely that OMT patients also experience many other somatic problems at higher rates and at relatively young ages. Sexual dysfunctiona common side effect of OMT medications as well as associated with ageingwas also a common complaint among OMT patients according to a meta-analysis, although the authors noted that differences in sample ages prevented proper comparisons, and only men were included [14].…”

Section: Introductionmentioning

confidence: 79%

Large and non-specific somatic disease burdens among ageing, long-term opioid maintenance treatment patients

Medved

Clausen

Bukten

et al. 2020

Subst Abuse Treat Prev Policy

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Objectives To describe and explore somatic disease burdens of ageing long-term patients in opioid maintenance treatment (OMT), a unique population emerging in countries offering OMT as a long-term treatment. Methods We used data from the Norwegian Cohort of Patient in Opioid Maintenance Treatment and Other Drug Treatment Study (NorComt). 156 patients enrolled for at least three of the past five years provided data during structured interviews, including on chronic conditions, somatic treatment received, mental distress (SCL-25), and treatment satisfaction. A somatic disease burden was calculated from a list measuring the recent severity of 16 somatic complaints. A hierarchical multiple linear regression analysis identified correlates of somatic disease burden. Results Over half of patients reported at least seven somatic complaints. Reported somatic disease burden was associated with higher mental distress, more chronic conditions, fewer years in OMT, and treatment dissatisfaction. Age was unrelated, and there were few gender differences. These five variables explained 43.6% of the variance in disease burden. Conclusion Long-term OMT patients experience a large range of somatic complaints, and at non-acute levels. As OMT secures longevity for opioid-dependent persons, the clinical focus must be adjusted from acute to chronic care. Providers must address how to optimize health and quality of life while in treatment, as treatment may last for many years.

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Section: Introductionmentioning

confidence: 79%

Large and non-specific somatic disease burdens among ageing, long-term opioid maintenance treatment patients

Medved

Clausen

Bukten

et al. 2020

Subst Abuse Treat Prev Policy

Self Cite

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“…The European Monitoring Centre for Drugs and Drug Addiction (18), in Europe, and the National Institute on Drug Abuse (20), in US, first sounded the alarm, raising concerns about the vulnerability of people with substance use disorders to COVID-19, especially because of opiates (e.g. heroin), synthetic opioids, and methamphetamine effects on the respiratory system and pulmonary health (21)(22)(23). Comorbidities, including cardiovascular and other respiratory diseases, have proven to worsen prognosis in patients with other coronaviruses affecting the respiratory system, such as SARS-CoV and MERS-CoV (24).…”

Section: Covid-19 Health Risks Associated To Psychotropic Drug Usementioning

confidence: 99%

New Trends of Substance Abuse During COVID-19 Pandemic: An International Perspective

2020

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“…The Norwegian health authorities [9] recommend exercise as an adjunct treatment for substance use disorders because, in addition to clinical benefits, it is cost-effective and accessible after the formal treatment system. Importantly, exercise reduces the risk of numerous preventable chronic diseases [10,11], of which people with substance use disorders already experience earlier and with more fatal consequences [12,13,14,15].…”

Section: Introductionmentioning

confidence: 99%

Inmates with Harmful Substance Use Increase Both Exercise and Nicotine Use Under Incarceration

Muller

Havnes

Rognli

et al. 2018

IJERPH

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Exercise is increasingly understood as an important resource for people who engage in harmful substance use, including those in prison. Little is known about how inmates adopt various health behaviors during incarceration, without interventions. This cross-sectional study analyzed self-reports from 1464 inmates in Norwegian prisons in 2013–2014, compared them according to harmful substance use pre-incarceration, and explored changes in exercise and nicotine use during incarceration. Results were presented in accordance with the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines. Inmates with harmful substance use reported higher rates of smoking, smokeless tobacco, and physical inactivity pre-incarceration than inmates without harmful use. However, inmates with harmful use also exhibited more behavioral changes: they adopted exercise, ceased smoking, and adopted smokeless tobacco at higher rates during incarceration than the non-harmful group, to the extent that inmates with harmful use exercised during incarceration more. Exercise is being taken up by a significant proportion of inmates, and may in particular be a replacement behavior for substance use. However, unhealthy behaviors also begin or are maintained. If prisons were used as an arena to facilitate healthy behaviors, the public health benefits to a marginalized group such as substance-using inmates could be substantial.

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Cardiovascular disease among people with drug use disorders

Abstract: Patients injecting drugs using prescribed methadone were at elevated risk for cardiovascular disease and should be monitored for CVD. Opioid medications should be evaluated in terms of their cardiovascular sequelae.

Cited by 33 publications

References 34 publications

Large and non-specific somatic disease burdens among ageing, long-term opioid maintenance treatment patients

Large and non-specific somatic disease burdens among ageing, long-term opioid maintenance treatment patients

New Trends of Substance Abuse During COVID-19 Pandemic: An International Perspective

Inmates with Harmful Substance Use Increase Both Exercise and Nicotine Use Under Incarceration

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