Cardiovascular Disease Projections in the United States Based on the 2020 Census Estimates

Mohebi, Reza; Chen, Chen; Ibrahim, Nasrien E.; McCarthy, Cian P.; Gaggin, Hanna K.; Singer, Daniel E.; Hyle, Emily P; Wasfy, Jason H.; Januzzi, James L.

doi:10.1016/j.jacc.2022.05.033

Cited by 164 publications

(64 citation statements)

References 38 publications

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“…A large future increase in the prevalence of cardiovascular diseases such as MI and HF is currently projected across the world, including Japan and the US. 30, 31 By 2060, in the hospital HF was more frequently observed in patients experiencing all-cause death and HF rehospitalization after discharge (53.6% vs. 20.2%; P<0.001; Table 1). The HFTP score (Figure 2) assessment revealed 291 (48.5%), 153 (25.5%), 110 (18.3%), and 46 (7.7%) patients with a score of 0, 1, 2, and 3, respectively.…”

Section: Np Concentrations In Amimentioning

confidence: 99%

“…Therefore, further risk stratification would be possible with US, it is estimated that the prevalence of MI and HF will increase by 16.9% and 33.4%, respectively, compared with 2025 levels (i.e., 4.9% of the population [16.0 million people] and 4.0% of the population [or 12.9 million people], respectively). 31 Because AMI is a major etiology of HF, 1,2 identifying AMI patients who are at a high risk of developing future HF is clinically relevant in the current "heart failure pandemic" era. 30,32 In this context, recent guidelines recommended (Class IIa) measuring plasma BNP or NT-proBNP concentrations to gain prognostic information in patients with non-STEMI; 8 however, the appropriate timing for evaluation of NP concentrations in AMI patients remains unclear.…”

Section: In-hospital Hf After Amimentioning

confidence: 99%

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Prognostic Value of Natriuretic Peptide Levels and In-Hospital Heart Failure Events in Patients With Acute Myocardial Infarction

Asada

Saito

Sato

et al. 2023

Circ J

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tion of patients with ST-segment elevation myocardial infarction (STEMI) predicted mortality, 10,11 whereas other reports indicated that NP concentrations during shortterm follow-up after AMI were more predictive than those at baseline. 12,13 In addition, acute HF often develops during hospitalization for AMI, 14 but its prognostic value in combination with NP concentrations is uncertain. 3,15 Thus, the aim of the present study was to evaluate the effects of elevated NP concentrations on admission and at the shortterm follow-up, and in-hospital HF events, individually and in combination, on clinical outcomes after discharge in patients with AMI. Methods Study PopulationThis was a retrospective, observational, bicenter study. [16][17][18][19][20][21] Between January 2012 and March 2020, 1,102 AMI patients I schemic heart disease, such as acute myocardial infarction (AMI), is a major underlying pathogenic factor in heart failure (HF), accounting for approximately 50% of cases in the current era, 1,2 and HF event is a strong predictor of worse outcomes among patients with AMI. 3,4 B-type natriuretic peptide (BNP) and N-terminal pro-BNP (NT-proBNP) are natriuretic peptides (NPs) secreted by the cardiac ventricles in response to end-diastolic pressure and volume, 5 and are widely used as diagnostic biomarkers for HF in clinical practice. 6 Elevated NP concentrations are associated with an increased risk of death and HF in patients with AMI, 5,7 and thus recent guidelines recommend measurement of NPs to gain prognostic information in patients with AMI. 8 However, the trajectory in BNP and NT-proBNP concentrations varies widely among patients, and the appropriate timing for NPs evaluation after AMI remains unclear. 9 For example, early studies demonstrated that the BNP concentration at the time of initial presenta-

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Section: Np Concentrations In Amimentioning

confidence: 99%

Section: In-hospital Hf After Amimentioning

confidence: 99%

Prognostic Value of Natriuretic Peptide Levels and In-Hospital Heart Failure Events in Patients With Acute Myocardial Infarction

Asada

Saito

Sato

et al. 2023

Circ J

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“…With the increasing prevalence of hypertension in adolescents, it is expected that the prevalence in young adults will also increase. In the United States, CVD projections estimate significant increases in CVD among adults in future decades, including hypertension (42). Detection and effective management of hypertension and elevated BP in adolescence, as well as primordial prevention beginning in early childhood, would have a substantial impact on stemming the rising tide of CVD in adults.…”

Section: Prevalence and Diagnosis Of Primary Hypertension In Childhoodmentioning

confidence: 99%

The enigma of primary hypertension in childhood

Falkner

2022

Front. Cardiovasc. Med.

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Beginning in the 1970s, hypertension in children and adolescents has been defined as systolic and/or diastolic blood pressure (BP) that is equal to or greater than the 95th percentile of the normal BP distribution in healthy children. The definition of hypertension in adults is based on longitudinal data that links a BP level with an increased risk for subsequent adverse outcomes related to hypertension including heart failure, kidney failure, stroke, or death. The statistical definition of hypertension continues to be used in childhood because there have been no data that link a BP level in childhood with a heightened risk for adverse outcomes in adulthood. Findings from clinical and epidemiologic research have advanced understanding of high BP in childhood. While hypertension in some children can be secondary to underlying kidney, cardiovascular, or endocrine disorder, it is now known that primary (essential) hypertension can be present in childhood. The prevalence of hypertension in childhood is approximately 2–5% and another 13–18% of children and adolescents have elevated BP and are at heightened risk for developing hypertension. The leading cause of childhood hypertension is primary hypertension, especially in adolescents. For children and adolescents with secondary hypertension, the treatment can focus on managing the underlying cause of hypertension. Less is known about managing primary hypertension in childhood, including diagnosis, evaluation, treatment, and possibilities for prevention. The phenotype of primary hypertension in childhood and recent findings will be discussed.

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“…Coronary artery disease (CAD) is a growing threat to global health in both developing and developed countries, with an increasing prevalence and morbidity every year [ 1 ]. By 2060, 28.7 million patients will be diagnosed with CAD, 12.9 million with heart failure, and 16.0 million with myocardial infarction in the United States alone [ 2 ]. CAD is a clinical manifestation of atherosclerosis—a systemic inflammatory process in the walls of the arteries combined with lipid accumulation in the matrix of the intima, which progresses slowly; thus, the effects of this disease are seen mainly in the elderly [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Investigation on the Association of Copper and Copper-to-Zinc-Ratio in Hair with Acute Coronary Syndrome Occurrence and Its Risk Factors

et al. 2022

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The prevalence of coronary artery disease (CAD) increases every year; however, the impact of microelements on its underlying cause—atherosclerosis—is still unclear. Copper plays numerous regulatory roles in cardiovascular health and was suggested to influence the classic risk factors for CAD. The copper-to-zinc-ratio (Cu/Zn-ratio) reflects systemic oxidative stress–one of the factors in the complex pathogenesis of atherosclerosis. Hair incorporates metal ions during its growth; thus, it reflects the metal exposure that occurred over the last 4–8 weeks. The aim of the presented study was to verify the association between Cu and Cu/Zn-ratio content and the occurrence of acute coronary syndrome (ACS) in the hair of 133 patients who underwent coronary angiography due to suspected ACS. Additionally, association between Cu and Cu/Zn-ratio and selected risk factors for CAD was analyzed. Neither Cu nor Cu/Zn-ratio levels were associated with the occurrence of ACS, regardless of its type (UA/NSTEMI/STEMI). We did not find a significant association between Cu content in hair and risk factors for CAD. The Cu/Zn-ratio in hair was significantly correlated only with body mass index. The relationship of Cu content and Cu/Zn-ratio in hair with CAD, its risk factors and ACS appears to be complex and requires further well-designed research.

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Cardiovascular Disease Projections in the United States Based on the 2020 Census Estimates

Cited by 164 publications

References 38 publications

Prognostic Value of Natriuretic Peptide Levels and In-Hospital Heart Failure Events in Patients With Acute Myocardial Infarction

Prognostic Value of Natriuretic Peptide Levels and In-Hospital Heart Failure Events in Patients With Acute Myocardial Infarction

The enigma of primary hypertension in childhood

Investigation on the Association of Copper and Copper-to-Zinc-Ratio in Hair with Acute Coronary Syndrome Occurrence and Its Risk Factors

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