2022
DOI: 10.3389/fonc.2022.976711
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Cardiovascular disease related death among patients with esophagus cancer: A population-based competing risk analysis

Abstract: The proportion of non-cancer death in patients with esophagus cancer (EC) still increasing, especially cardiovascular disease (CVD) related death. The aim of this study was assess non-cancer causes of death and identified independent risk factors of CVD related death in EC patients. Patients diagnosed with EC were extracted from the Surveillance, Epidemiology, and End Result database (SEER) database for analysis. Standardized mortality rates (SMRs) for non-EC deaths were calculated, the risk of death were asse… Show more

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Cited by 5 publications
(2 citation statements)
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“…Therefore, the risk of postoperative cardiovascular events in GBC patients should be considered, such as the prevention of acute hypertension and arrhythmia in postoperative care. On the other hand, received chemotherapy were protective factor for non cancer death in our analysis, consistent with previous studies 39 , 46 , 47 . This does not seem to fit with the common belief that chemotherapy causes cardiotoxicity and increases the risk of CVD.…”
Section: Discussionsupporting
confidence: 92%
See 1 more Smart Citation
“…Therefore, the risk of postoperative cardiovascular events in GBC patients should be considered, such as the prevention of acute hypertension and arrhythmia in postoperative care. On the other hand, received chemotherapy were protective factor for non cancer death in our analysis, consistent with previous studies 39 , 46 , 47 . This does not seem to fit with the common belief that chemotherapy causes cardiotoxicity and increases the risk of CVD.…”
Section: Discussionsupporting
confidence: 92%
“…This does not seem to fit with the common belief that chemotherapy causes cardiotoxicity and increases the risk of CVD. This may be due to that patients who receive regular chemotherapy can receive better health monitoring during treatment and receive more timely intervention when at healthy risk to avoid subsequent adverse events 47 . However, the underlying mechanism why chemotherapy improves non cancer death outcomes in GBC patients has not been clarified, and further studies still needed.…”
Section: Discussionmentioning
confidence: 99%