Cardiovascular Diseases and Alimentary Comparison Study

Hekman, P. R. W.; Bos, Angelo; Cunha, Roberto S.; Moriguchi, Yukio

doi:10.1097/00005344-199000168-00007

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“…In five studies the association with BP was examined for urinary taurine [49], [50], [55] or serum taurine [45], [56] which the authors regarded as a biomarker of seafood protein intake (data not in table). Three of these studies were conducted among Asian populations (n = 705 to n = 1,681) [45], [49], [50], whereas the others were conducted in Brazil (n = 57) and USA (n = 168) [55], [56]. In all these studies inverse associations with BP were observed, but no information about the strength of the associations was given.…”

Section: Resultsmentioning

confidence: 99%

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Dietary Protein and Blood Pressure: A Systematic Review

et al. 2010

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BackgroundElevated blood pressure (BP), which is a major risk factor for cardiovascular disease, is highly prevalent worldwide. Recently, interest has grown in the role of dietary protein in human BP. We performed a systematic review of all published scientific literature on dietary protein, including protein from various sources, in relation to human BP.Methodology/Principal FindingsWe performed a MEDLINE search and a manual search to identify English language studies on the association between protein and blood pressure, published before June 2010. A total of 46 papers met the inclusion criteria. Most observational studies showed no association or an inverse association between total dietary protein and BP or incident hypertension. Results of biomarker studies and randomized controlled trials indicated a beneficial effect of protein on BP. This beneficial effect may be mainly driven by plant protein, according to results in observational studies. Data on protein from specific sources (e.g. from fish, dairy, grain, soy, and nut) were scarce. There was some evidence that BP in people with elevated BP and/or older age could be more sensitive to dietary protein.Conclusions/SignificanceIn conclusion, evidence suggests a small beneficial effect of protein on BP, especially for plant protein. A blood pressure lowering effect of protein may have important public health implications. However, this warrants further investigation in randomized controlled trials. Furthermore, more data are needed on protein from specific sources in relation to BP, and on the protein-BP relation in population subgroups.

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Section: Resultsmentioning

confidence: 99%

“…Three of these studies were conducted among Asian populations (n = 705 to n = 1,681) [45] , [49] , [50] , whereas the others were conducted in Brazil (n = 57) and USA (n = 168). [55] , [56] In all these studies inverse associations with BP were observed, but no information about the strength of the associations was given.…”

Section: Resultsmentioning

confidence: 99%