Cardiovascular Effects of Successful Renal Transplantation: A 30-Month Study on Left Ventricular Morphology, Systolic and Diastolic Functions

Dudziak, Maria; Dębska‐Ślizień, Alicja; Rutkowski, Bolesław

doi:10.1016/j.transproceed.2004.12.201

Cited by 39 publications

(35 citation statements)

References 12 publications

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“…We used the recommendations of the American Society of Echocardiography 13 and observed a high frequency at baseline assessment (57.5%) in this study; after six months of transplantation, there was a significant 43% reduction of this frequency, when compared to baseline assessment. Studies carried out without the use of tissue Doppler have not demonstrated the impact of kidney transplantation on diastolic function 22,31 ; however, a recent study using tissue Doppler as a criterion for the quantification of diastolic function showed similar results to the ones of the present study 17 .…”

Section: Discussionsupporting

confidence: 78%

Estudo das alterações ecocardiográficas nos primeiros seis meses após o transplante renal

Souza¹,

Bezerra²,

Sousa³

et al. 2012

Arq. Bras. Cardiol.

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Section: Discussionsupporting

confidence: 78%

Estudo das alterações ecocardiográficas nos primeiros seis meses após o transplante renal

Souza¹,

Bezerra²,

Sousa³

et al. 2012

Arq. Bras. Cardiol.

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“…Also an improvement in central arterial stiffness was observed after a year of follow-up [69,70]. This is in line with the other evidence that cardiac function in DM transplant candidates is carefully evaluated prior to transplantation and LV systolic, diastolic function and arterial compliance improves shortly after a successful renal transplant [71][72][73][74][75]. It was also concluded that assessment of arterial stiffness may improve pre-transplantation risk assessment both in donors and recipients [70].…”

Section: Risk In Kidney Transplanted Patientssupporting

confidence: 69%

Cardiovascular Risk Assessment in Diabetes and Chronic Kidney Diseases: A New Insight and Emerging Strategies

Khoshdel¹

2012

Cardiovascular Risk Factors

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“…Left ventricular hypertrophy (LVH) is a common feature of patients with ESRD, a component of uremic cardiomyopathy, and an independent risk factor for sudden cardiac death, heart failure, and cardiac arrhythmias in the general population and dialysis patients (2,3). Furthermore, successful renal transplantation (RT) is associated with lower cardiovascular morbidity and mortality compared with patients who remain on the transplant waiting list (4) and has been reportedly associated with significant echocardiographic regression of LVH (5,6).…”

mentioning

confidence: 99%

Renal Transplantation Is Not Associated with Regression of Left Ventricular Hypertrophy

Patel¹,

Mark²,

Johnston³

et al. 2008

Clinical Journal of the American Society of Nephrology

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Background and objectives: Patients with end-stage renal failure (ESRD) have an increased risk of premature cardiovascular (CV) disease. Left ventricular hypertrophy is an independent risk factor for CV events and death in ESRD. Renal transplantation has been associated with reduction in CV risk and echocardiographic regression of left ventricular hypertrophy. However, echocardiography overestimates LV mass in ESRD patients. Cardiac magnetic resonance (CMR) provides more detailed, volume-independent, measures of cardiac structure. Changes in LV mass measured by CMR after renal transplantation were studied.Design, setting, participants, & measurements: Fifty patients underwent CMR on two occasions. Twenty-five were transplanted before the second scan. CMR was performed to measure LV mass index (LVMI), ejection fraction, end-diastolic and end-systolic volumes. Changes were expressed as percentage change over time. Patients with CV events between scans (e.g., acute coronary syndrome, myocardial infarction) were excluded. All transplant patients had serum creatinine <150 mol/L.Results: There was no significant change in LVMI between patients who underwent renal transplantation and those who remained on dialysis (transplanted mean, 2.75%/yr, ؎ 9.1 versus dialysis, ؊3.6%/yr ؎ 16.7). In addition, there were no significant changes in end-diastolic volume (transplant, 0.1%/yr ؎ 19.5 versus not transplanted, ؊3.4%/yr ؎ 31.5), end-systolic volume (transplanted mean, 15.2%/yr ؎ 65.2 versus not transplanted, 3.0%/yr ؎ 55.5), or ejection fraction (transplant, 2.1%/yr ؎ 11.9 versus not transplanted, ؊0.4%/yr ؎ 5.3).Conclusions: Renal transplantation is not associated with significant regression of LVMI on CMR compared with patients who remain on the transplant waiting list.

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Cardiovascular Effects of Successful Renal Transplantation: A 30-Month Study on Left Ventricular Morphology, Systolic and Diastolic Functions

Cited by 39 publications

References 12 publications

Estudo das alterações ecocardiográficas nos primeiros seis meses após o transplante renal

Estudo das alterações ecocardiográficas nos primeiros seis meses após o transplante renal

Cardiovascular Risk Assessment in Diabetes and Chronic Kidney Diseases: A New Insight and Emerging Strategies

Renal Transplantation Is Not Associated with Regression of Left Ventricular Hypertrophy

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