2007
DOI: 10.1016/j.jacc.2006.08.042
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Cardiovascular Manifestations of Hyperthyroidism Before and After Antithyroid Therapy

Abstract: Cardiovascular abnormalities are common in patients with overt hyperthyroidism at presentation, but some persist despite effective antithyroid therapy.

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Cited by 132 publications
(150 citation statements)
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References 38 publications
(37 reference statements)
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“…All-cause mortality is increased by 20% in subjects with hyperthyroidism [2]. Cardiovascular symptoms including palpitations and dyspnoea are common, irrespective of background cardiovascular disease, and do not resolve in all individuals even after return to the euthyroid state [3]. A schematic of the cardiac pathology of Graves' hyperthyroidism is provided in Figure 1.…”
Section: Introductionmentioning
confidence: 99%
“…All-cause mortality is increased by 20% in subjects with hyperthyroidism [2]. Cardiovascular symptoms including palpitations and dyspnoea are common, irrespective of background cardiovascular disease, and do not resolve in all individuals even after return to the euthyroid state [3]. A schematic of the cardiac pathology of Graves' hyperthyroidism is provided in Figure 1.…”
Section: Introductionmentioning
confidence: 99%
“…Thus, decreased serum TSH levels have been reported to be associated with surrogate markers of cardiovascular mortality including carotid wall thickness (1), atrial fibrillation (2, 3), high plasma fibrinogen levels (4), and left ventricular hypertrophy (5,6). However, results of studies on the association between decreased serum TSH levels or subclinical hyperthyroidism (3,(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18) and mortality are conflicting. With respect to cardiovascular mortality, most studies (3,11,12,18) and all meta-analyses (10,14,17) detected no association between decreased serum TSH levels or hyperthyroidism and mortality, while two studies did detect an association (7,9).…”
Section: Introductionmentioning
confidence: 99%
“…However, results of studies on the association between decreased serum TSH levels or subclinical hyperthyroidism (3,(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18) and mortality are conflicting. With respect to cardiovascular mortality, most studies (3,11,12,18) and all meta-analyses (10,14,17) detected no association between decreased serum TSH levels or hyperthyroidism and mortality, while two studies did detect an association (7,9). Regarding all-cause mortality, one study (7) demonstrated an increased mortality risk in subjects with decreased serum TSH levels, whereas two others did not (12,16).…”
Section: Introductionmentioning
confidence: 99%
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