Cardiovascular morbidity–mortality associated to ankle-brachial index in the general population

Lahoz, Carlos; Barrionuevo, María Bellido; García-Fernández, T.; Vicente, Ignacio; García-Iglesias, M.F.; Mostaza, José María

doi:10.1016/j.rceng.2013.10.003

Cited by 2 publications

(1 citation statement)

References 22 publications

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“…In comparison to angiography, the gold standard for detecting atherosclerosis in the lower limbs arteries, low ABI (<0.9) has good sensitivity (between 69% and 79%) and excellent specificity (between 83% to 99%) [3]. PAD is associated with increased cardiovascular and overall morbidity and deaths in the general population and among hemodialysis patients [4] [5]. In a study by Ono et al [5], the risk for cardiovascular mortality was 5.9-fold higher in dialysis patients with low ABI (<0.9).…”

Section: Introductionmentioning

confidence: 99%

Peripheral Arterial Disease among Patient Undergoing Maintenance Hemodialysis in Dakar (Senegal)

Lengani¹,

Cissé²,

Yattara³

et al. 2021

OJNeph

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Background: Peripheral arterial disease (PAD) is common in patients with chronic kidney disease (CKD). It is a surrogate marker of generalized atherosclerosis. In sub-Saharan Africa, PAD remains understudied in CKD. Ankle-brachial index (ABI) is a non-invasive and cost-effective tool to diagnose PAD. Objectives: Our aim was to determine the prevalence and associated risk factors for PAD in hemodialysis patients. Patients and Methods: We conducted a cross-sectional study from July 1 to December 31, 2012 in the department of Nephrology of the University Hospital Aristide le Dantec of Dakar. All consenting patients, aged above 18 years, on hemodialysis for at least 6 months were included. ABI measurements were performed using a handled pulse doppler. PAD was defined as an ABI of <0.9 or the history of surgical revascularization and/or amputation due to vascular disease. The patients were divided into two groups according to the presence or not of PAD. Standard blood tests and anthropometrical parameters were recorded. Results: A total of 53 patients with a mean age of 49.15 ± 15.18 were included. The sex ratio was 0.70. Hypertension (83.01%), low HDL-cholesterol (26.41%) and cigarette smoking (20.75%) were the main cardiovascular risk factors. Prevalence of PAD was 47.16%. Among patients with PAD, 52% had no suggestive symptoms. Lower pre-dialysis (p = 0.0384) and post-dialysis (p = 0.0447) diastolic blood pressure (BP) were significantly associated with PAD. The conventional risk factors (tobacco consumption, diabetes, alcohol consumption, dyslipidemia, hypertension, age), iPTH and CRP levels were not

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