Cardiovascular outcomes after percutaneous coronary intervention on bifurcation lesions with moderate to severe coronary calcium: A <scp>single‐center</scp> registry study

Murphy, Jonathan; Patel, Nileshkumar; Vengrenyuk, Yuliya; Okamoto, Naotaka; Barman, Nitin; Sweeny, Joseph; Kapur, Vishal; Hasan, Choudhury; Ramanathan, Krishnan; Vijay, Pooja; Jhaveri, Vaishvi; Dangas, George; Mehran, Roxana; Aquino, Melissa; Baber, Usman; Sharma, Samin K.; Kini, Annapoorna

doi:10.1002/ccd.29069

Cited by 6 publications

(1 citation statement)

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“…These concerns are amplified in the left main as the consequences of complications are potentially life‐threatening. Anatomical factors that have been identified to adversely influence endpoints include significant calcification 5 and increased plaque burden 6 . Procedural variation at several stages of provisional stenting also impacts outcomes, with increased rates of SV stenting required following SV predilation 7 and improved SV flow recovery with the use of jailed wires 8 .…”

Section: Introductionmentioning

confidence: 99%

Impact of technique on bifurcation stent outcomes in the European Bifurcation Club Left Main Coronary Trial

Arunothayaraj

Lassen

Clesham

et al. 2023

Cathet Cardio Intervent

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Background Techniques for provisional and dual‐stent left main bifurcation stenting require optimization. Aim To identify technical variables influencing procedural outcomes and periprocedural myocardial infarction following left main bifurcation intervention. Methods Procedural and outcome data were analyzed in 438 patients from the per‐protocol cohort of the European Bifurcation Club Left Main Trial (EBC MAIN). These patients were randomized to the provisional strategy or a compatible dual‐stent extension (T, T‐and‐protrude, or culotte). Results Mean age was 71 years and 37.4% presented with an acute coronary syndrome. Transient reduction of side vessel thrombolysis in myocardial infarction flow occurred after initial stent placement in 5% of procedures but was not associated with periprocedural myocardial infarction. Failure to rewire a jailed vessel during any strategy was more common when jailed wires were not used (9.5% vs. 2.5%, odds ratio [OR]: 6.4, p = 0.002). In the provisional cohort, the use of the proximal optimization technique was associated with less subsequent side vessel intervention (23.3% vs. 41.9%, OR: 0.4, p = 0.048). Side vessel stenting was predominantly required for dissection, which occurred more often following side vessel preparation (15.3% vs. 4.4%, OR: 3.1, p = 0.040). Exclusive use of noncompliant balloons for kissing balloon inflation was associated with reduced need for side vessel intervention in provisional cases (20.5% vs. 38.5%, OR: 0.4, p = 0.013), and a reduced risk of periprocedural myocardial infarction across all strategies (2.9% vs. 7.7%, OR: 0.2, p = 0.020). Conclusion When performing provisional or compatible dual‐stent left main bifurcation intervention, jailed wire use is associated with successful jailed vessel rewiring. Side vessel preparation in provisional patients is linked to increased side vessel dissection requiring stenting. Use of the proximal optimization technique may reduce the need for additional side vessel intervention, and noncompliant balloon use for kissing balloon inflation is associated with a reduction in both side vessel stenting and periprocedural myocardial infarction. Clinical Trial Registration http://ClinicalTrials.gov Identifier NCT02497014.

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