2023
DOI: 10.1152/japplphysiol.00045.2023
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Cardiovascular responses to static handgrip exercise and postexercise ischemia in heart failure with preserved ejection fraction

Abstract: Exercise intolerance is a well-described characteristic of heart failure with preserved ejection fraction (HFpEF), but whether disease-related changes in autonomic function contribute to impaired cardiovascular control during exercise is not well understood. Thus, we used a combination of static handgrip exercise (HG) and post-exercise ischemia (PEI) to examine the pressor response to exercise and isolate the skeletal muscle metaboreflex, respectively. Mean arterial pressure (MAP), heart rate (HR), cardiac out… Show more

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